×
Entrez Id:
5426
Gene Symbol:
POLE
POLE
0.600
CausalMutation
disease
CLINVAR
Germline and somatic polymerase ε and δ mutations define a new class of hypermutated colorectal and endometrial cancers.
23447401
2013
×
Entrez Id:
5426
Gene Symbol:
POLE
POLE
0.600
CausalMutation
disease
CLINVAR
Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas.
23263490
2013
×
Entrez Id:
5426
Gene Symbol:
POLE
POLE
0.600
CausalMutation
disease
CLINVAR
Frequency and phenotypic spectrum of germline mutations in POLE and seven other polymerase genes in 266 patients with colorectal adenomas and carcinomas.
25529843
2015
×
Entrez Id:
5426
Gene Symbol:
POLE
POLE
0.600
CausalMutation
disease
CLINVAR
Okazaki fragment maturation in yeast. II. Cooperation between the polymerase and 3'-5'-exonuclease activities of Pol delta in the creation of a ligatable nick.
12424237
2003
×
Entrez Id:
5426
Gene Symbol:
POLE
POLE
0.600
CausalMutation
disease
CLINVAR
Germline variants in POLE are associated with early onset mismatch repair deficient colorectal cancer.
25370038
2015
×
Entrez Id:
5426
Gene Symbol:
POLE
POLE
0.600
GeneticVariation
disease
CLINVAR
Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas.
23263490
2013
×
Entrez Id:
5426
Gene Symbol:
POLE
POLE
0.600
CausalMutation
disease
CLINVAR
New insights into POLE and POLD1 germline mutations in familial colorectal cancer and polyposis.
24501277
2014
×
Entrez Id:
5426
Gene Symbol:
POLE
POLE
0.600
SusceptibilityMutation
disease
CLINVAR
×
Entrez Id:
5426
Gene Symbol:
POLE
POLE
0.600
GeneticVariation
disease
CLINVAR
Germline and somatic polymerase ε and δ mutations define a new class of hypermutated colorectal and endometrial cancers.
23447401
2013
×
Entrez Id:
5426
Gene Symbol:
POLE
POLE
0.600
CausalMutation
disease
CLINVAR
A method to select for mutator DNA polymerase deltas in Saccharomyces cerevisiae.
16699561
2006
×
Entrez Id:
5426
Gene Symbol:
POLE
POLE
0.600
CausalMutation
disease
CLINVAR
Immunogenomics of Hypermutated Glioblastoma: A Patient with Germline POLE Deficiency Treated with Checkpoint Blockade Immunotherapy.
27683556
2016
×
Entrez Id:
4092
Gene Symbol:
SMAD7
SMAD7
0.100
GeneticVariation
disease
GWASCAT
Discovery of common and rare genetic risk variants for colorectal cancer.
30510241
2019
×
Entrez Id:
999
Gene Symbol:
CDH1
CDH1
0.100
GeneticVariation
disease
GWASCAT
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer.
19011631
2008
×
Entrez Id:
2289
Gene Symbol:
FKBP5
FKBP5
0.100
GeneticVariation
disease
GWASCAT
Discovery of common and rare genetic risk variants for colorectal cancer.
30510241
2019
BAALC-AS1
0.100
GeneticVariation
disease
GWASCAT
Genetic susceptibility markers for a breast-colorectal cancer phenotype: Exploratory results from genome-wide association studies.
29698419
2018
×
Entrez Id:
5462
Gene Symbol:
POU5F1B
POU5F1B
0.100
GeneticVariation
disease
GWASCAT
A new GWAS and meta-analysis with 1000Genomes imputation identifies novel risk variants for colorectal cancer.
25990418
2015
×
Entrez Id:
100750225
Gene Symbol:
PCAT1
PCAT1
0.100
GeneticVariation
disease
GWASCAT
Association analyses identify 31 new risk loci for colorectal cancer susceptibility.
31089142
2019
×
Entrez Id:
100750225
Gene Symbol:
PCAT1
PCAT1
0.100
GeneticVariation
disease
GWASCAT
Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
23266556
2013
×
Entrez Id:
894
Gene Symbol:
CCND2
CCND2
0.100
GeneticVariation
disease
GWASCAT
Novel Common Genetic Susceptibility Loci for Colorectal Cancer.
29917119
2019
×
Entrez Id:
5462
Gene Symbol:
POU5F1B
POU5F1B
0.100
GeneticVariation
disease
GWASCAT
Large-scale genetic study in East Asians identifies six new loci associated with colorectal cancer risk.
24836286
2014
×
Entrez Id:
54596
Gene Symbol:
L1TD1
L1TD1
0.100
GeneticVariation
disease
GWASCAT
Large-Scale Genome-Wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer.
30529582
2019
×
Entrez Id:
29086
Gene Symbol:
BABAM1
BABAM1
0.100
GeneticVariation
disease
GWASCAT
Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.
27197191
2016
×
Entrez Id:
4093
Gene Symbol:
SMAD9
SMAD9
0.100
GeneticVariation
disease
GWASCAT
Association analyses identify 31 new risk loci for colorectal cancer susceptibility.
31089142
2019
×
Entrez Id:
6311
Gene Symbol:
ATXN2
ATXN2
0.100
GeneticVariation
disease
GWASCAT
Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.
26621817
2015
×
Entrez Id:
143187
Gene Symbol:
VTI1A
VTI1A
0.100
GeneticVariation
disease
GWASCAT
Large-Scale Genome-Wide Association Study of East Asians Identifies Loci Associated With Risk for Colorectal Cancer.
30529582
2019