Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 761
Gene Symbol: CA3
CA3 		0.500 Biomarker disease CTD_human Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. 25231249 2015
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		0.500 Biomarker disease CTD_mouse Inhibition of P-glycoprotein Gene Expression and Function Enhances Triptolide-induced Hepatotoxicity in Mice. 26134275 2015
Entrez Id: 761
Gene Symbol: CA3
CA3 		0.500 Biomarker disease CTD_mouse Characterization of chemically induced liver injuries using gene co-expression modules. 25226513 2014
Entrez Id: 5243
Gene Symbol: ABCB1
ABCB1 		0.500 Biomarker disease CTD_human Phenotypic and genotypic assessment of concomitant drug-induced toxic effects in liver, kidney and blood. 20623750 2011
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1 		0.300 Therapeutic disease CTD_human Triptolide impairs thioredoxin system by suppressing Notch1-mediated PTEN/Akt/Txnip signaling in hepatocytes. 30394310 2019
Entrez Id: 7100
Gene Symbol: TLR5
TLR5 		0.300 Biomarker disease CTD_human TLR5 silencing reduced hyperammonaemia-induced liver injury by inhibiting oxidative stress and inflammation responses via inactivating NF-κB and MAPK signals. 30508503 2019
Entrez Id: 3827
Gene Symbol: KNG1
KNG1 		0.300 Biomarker disease CTD_human Bradykinin contributes to immune liver injury via B2R receptor-mediated pathways in trichloroethylene sensitized mice: A role in Kupffer cell activation. 30685357 2019
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2 		0.300 Biomarker disease CTD_human Bradykinin contributes to immune liver injury via B2R receptor-mediated pathways in trichloroethylene sensitized mice: A role in Kupffer cell activation. 30685357 2019
Entrez Id: 5580
Gene Symbol: PRKCD
PRKCD 		0.300 Therapeutic disease CTD_human Protein kinase Cδ knockout mice are protected from cocaine-induced hepatotoxicity. 30393195 2019
Entrez Id: 4780
Gene Symbol: NFE2L2
NFE2L2 		0.300 Therapeutic disease CTD_human Nrf2 Activation Ameliorates Hepatotoxicity Induced by a Heme Synthesis Inhibitor. 30215777 2019
Entrez Id: 8431
Gene Symbol: NR0B2
NR0B2 		0.300 Therapeutic disease CTD_human Hepatocyte SHP deficiency protects mice from acetaminophen-evoked liver injury in a JNK-signaling regulation and GADD45β-dependent manner. 29943110 2018
Entrez Id: 407000
Gene Symbol: MIR218-1
MIR218-1 		0.300 Biomarker disease CTD_human Identification of Specific MicroRNA Biomarkers in Early Stages of Hepatocellular Injury, Cholestasis, and Steatosis in Rats. 30125006 2018
Entrez Id: 1571
Gene Symbol: CYP2E1
CYP2E1 		0.300 Biomarker disease CTD_human Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury. 28762043 2018
Entrez Id: 3727
Gene Symbol: JUND
JUND 		0.300 Biomarker disease CTD_human Embracing the Dark Side: Computational Approaches to Unveil the Functionality of Genes Lacking Biological Annotation in Drug-Induced Liver Injury. 30515189 2018
Entrez Id: 283120
Gene Symbol: H19
H19 		0.300 Biomarker disease CTD_human Embracing the Dark Side: Computational Approaches to Unveil the Functionality of Genes Lacking Biological Annotation in Drug-Induced Liver Injury. 30515189 2018
Entrez Id: 2494
Gene Symbol: NR5A2
NR5A2 		0.300 Biomarker disease CTD_human LRH-1 regulates hepatic lipid homeostasis and maintains arachidonoyl phospholipid pools critical for phospholipid diversity. 29515023 2018
Entrez Id: 1559
Gene Symbol: CYP2C9
CYP2C9 		0.300 Biomarker disease CTD_human Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury. 28762043 2018
Entrez Id: 2081
Gene Symbol: ERN1
ERN1 		0.300 Biomarker disease CTD_human Inositol-Requiring Enzyme 1 Alpha Endoribonuclease Specific Inhibitor STF-083010 Alleviates Carbon Tetrachloride Induced Liver Injury and Liver Fibrosis in Mice. 30538632 2018
Entrez Id: 1544
Gene Symbol: CYP1A2
CYP1A2 		0.300 Biomarker disease CTD_human Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury. 28762043 2018
Entrez Id: 1869
Gene Symbol: E2F1
E2F1 		0.300 Biomarker disease CTD_human Embracing the Dark Side: Computational Approaches to Unveil the Functionality of Genes Lacking Biological Annotation in Drug-Induced Liver Injury. 30515189 2018
Entrez Id: 1557
Gene Symbol: CYP2C19
CYP2C19 		0.300 Biomarker disease CTD_human Customised in vitro model to detect human metabolism-dependent idiosyncratic drug-induced liver injury. 28762043 2018
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1 		0.300 Biomarker disease CTD_human Embracing the Dark Side: Computational Approaches to Unveil the Functionality of Genes Lacking Biological Annotation in Drug-Induced Liver Injury. 30515189 2018
Entrez Id: 24145
Gene Symbol: PANX1
PANX1 		0.300 Biomarker disease CTD_human Protective effect of genetic deletion of pannexin1 in experimental mouse models of acute and chronic liver disease. 29246445 2018
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.300 Biomarker disease CTD_human Metformin treatment prevents SREBP2-mediated cholesterol uptake and improves lipid homeostasis during oxidative stress-induced atherosclerosis. 29499335 2018
Entrez Id: 406884
Gene Symbol: MIRLET7B
MIRLET7B 		0.300 Biomarker disease CTD_human Identification of Specific MicroRNA Biomarkers in Early Stages of Hepatocellular Injury, Cholestasis, and Steatosis in Rats. 30125006 2018