Gene: POU4F3 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5459
Gene Symbol: POU4F3
POU4F3 		0.360 GeneticVariation disease BEFREE DFNA15 is the third cochleovestibular disorder, after DFNA9 and DFNA11, in the autosomal dominant nonsyndromic hearing impairment. 19372648 2009
Entrez Id: 5459
Gene Symbol: POU4F3
POU4F3 		0.360 GeneticVariation disease BEFREE A mutation in the POU4F3 gene (BRN-3.1, BRN3C) is responsible for DFNA15 (MIM 602459), autosomal-dominant nonsyndromic hearing loss. 14585957 2003
Entrez Id: 5459
Gene Symbol: POU4F3
POU4F3 		0.360 Biomarker disease CLINGEN A novel frameshift mutation of POU4F3 gene associated with autosomal dominant non-syndromic hearing loss. 20434433 2010
Entrez Id: 5459
Gene Symbol: POU4F3
POU4F3 		0.360 Biomarker disease CLINGEN A novel missense variant in the nuclear localization signal of POU4F3 causes autosomal dominant non-syndromic hearing loss. 28790396 2017
Entrez Id: 5459
Gene Symbol: POU4F3
POU4F3 		0.360 Biomarker disease CLINGEN A Novel Nonsense Mutation of POU4F3 Gene Causes Autosomal Dominant Hearing Loss. 27999687 2016
Entrez Id: 5459
Gene Symbol: POU4F3
POU4F3 		0.360 Biomarker disease CLINGEN Deafness gene expression patterns in the mouse cochlea found by microarray analysis. 24676347 2014
Entrez Id: 5459
Gene Symbol: POU4F3
POU4F3 		0.360 Biomarker disease CLINGEN Exome sequencing identifies POU4F3 as the causative gene for a large Chinese family with non-syndromic hearing loss. 27535032 2017
Entrez Id: 5459
Gene Symbol: POU4F3
POU4F3 		0.360 Biomarker disease CLINGEN Genetic etiology study of the non-syndromic deafness in Chinese Hans by targeted next-generation sequencing. 23767834 2013
Entrez Id: 5459
Gene Symbol: POU4F3
POU4F3 		0.360 Biomarker disease CLINGEN Inhibition of Myo6 gene expression by co‑expression of a mutant of transcription factor POU4F3 (BRN‑3C) in hair cells. 24535414 2014
Entrez Id: 5459
Gene Symbol: POU4F3
POU4F3 		0.360 Biomarker disease CLINGEN Missense mutations in POU4F3 cause autosomal dominant hearing impairment DFNA15 and affect subcellular localization and DNA binding. 18228599 2008
Entrez Id: 5459
Gene Symbol: POU4F3
POU4F3 		0.360 Biomarker disease BEFREE Moreover, new variants in genes such as COCH, MYO7A and POU4F3 are associated with nonsyndromic deafness and vestibular dysfunction. 24275721 2014
Entrez Id: 5459
Gene Symbol: POU4F3
POU4F3 		0.360 Biomarker disease CLINGEN Mutation in transcription factor POU4F3 associated with inherited progressive hearing loss in humans. 9506947 1998
Entrez Id: 5459
Gene Symbol: POU4F3
POU4F3 		0.360 GeneticVariation disease BEFREE Mutations in the POU class 4 transcription factor 3 <i>(POU4F3)</i> are known to cause autosomal dominant nonsyndromic hearing loss linked to the loci of DFNA15. 29850532 2018
Entrez Id: 5459
Gene Symbol: POU4F3
POU4F3 		0.360 Biomarker disease CLINGEN Mutations in the POU class 4 transcription factor 3 <i>(POU4F3)</i> are known to cause autosomal dominant nonsyndromic hearing loss linked to the loci of DFNA15. 29850532 2018
Entrez Id: 5459
Gene Symbol: POU4F3
POU4F3 		0.360 GeneticVariation disease BEFREE Of the 23 probands, six had mutations in DFNA genes [WFS1 (n = 2), COCH, ACTG1, TMC1, and POU4F3] known to cause autosomal dominant nonsyndromic hearing loss. 25388789 2014
Entrez Id: 5459
Gene Symbol: POU4F3
POU4F3 		0.360 Biomarker disease CLINGEN POU4F3 mutation screening in Japanese hearing loss patients: Massively parallel DNA sequencing-based analysis identified novel variants associated with autosomal dominant hearing loss. 28545070 2017
Entrez Id: 5459
Gene Symbol: POU4F3
POU4F3 		0.360 Biomarker disease CLINGEN Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development. 8637595 1996
Entrez Id: 5459
Gene Symbol: POU4F3
POU4F3 		0.360 GeneticVariation disease BEFREE SNP linkage analysis and whole exome sequencing identify a novel POU4F3 mutation in autosomal dominant late-onset nonsyndromic hearing loss (DFNA15). 24260153 2013
Entrez Id: 5459
Gene Symbol: POU4F3
POU4F3 		0.360 Biomarker disease CLINGEN SNP linkage analysis and whole exome sequencing identify a novel POU4F3 mutation in autosomal dominant late-onset nonsyndromic hearing loss (DFNA15). 24260153 2013
Entrez Id: 5459
Gene Symbol: POU4F3
POU4F3 		0.360 Biomarker disease CLINGEN Transcription profiling of inner ears from Pou4f3(ddl/ddl) identifies Gfi1 as a target of the Pou4f3 deafness gene. 15254021 2004
Entrez Id: 5459
Gene Symbol: POU4F3
POU4F3 		0.360 Biomarker disease CLINGEN Transcriptome profiling of induced hair cells (iHCs) generated by combined expression of Gfi1, Pou4f3 and Atoh1 during embryonic stem cell differentiation. 26697340 2015