Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.370 AlteredExpression disease BEFREE Our in vivo results demonstrated that Gln treatment reduced ET release (as indicated by cell-free-DNA content and myeloperoxidase activity), decreased lung inflammation (reductions in interferon-γ and increases in interleukin-10 levels), and improved lung morpho-function (decreased static lung elastance and alveolar collapse) in comparison with ARDS animals treated with saline. 31013737 2019
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.370 AlteredExpression disease BEFREE We demonstrate that KB treatment attenuated cigarette smoke-induced lung inflammation as shown by reductions in levels of BAL IFNγ, CXCL9, CXCL10, CCL5, IL-6, G-CSF, and IL-17. 28506308 2017
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.370 Biomarker disease BEFREE Notably, sensitization of IL-10-deficient mice with OVA/Alum/CpG resulted in the development of neutrophilic lung inflammation associated with IFNγ production. 28220116 2017
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.370 Biomarker disease BEFREE Pulmonary inflammation in mice with collagen-induced arthritis is conditioned by complete Freund's adjuvant and regulated by endogenous IFN-γ. 22930199 2012
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.370 Biomarker disease BEFREE Regulation of neutrophils by interferon-γ limits lung inflammation during tuberculosis infection. 21967766 2011
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.370 Biomarker disease CTD_human Expansion of CD4(+) CD25(+) and CD25(-) T-Bet, GATA-3, Foxp3 and RORγt cells in allergic inflammation, local lung distribution and chemokine gene expression. 21625544 2011
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.370 AlteredExpression disease BEFREE The fatal lung inflammation is associated with high-level induction of interferon-gamma and its inducible inflammatory chemokines, suggesting the involvement of a T-helper-1 immune response. 20363924 2010
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.370 Biomarker disease BEFREE In the present study, we surprisingly observed that C. trachomatis mouse pneumonitis MoPn-infected IFN-gamma gene knockout (KO) mice mounted strong DTH responses following foopad challenge with inactivated organisms. 10556835 1999