Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
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0.370 | Biomarker | disease | BEFREE | Myeloid differentiation primary response 88 (MyD88) is involved in gram positive bacteria-induced lung inflammation by Toll-like receptors (TLRs). | 30802676 | 2019 | ||||
|
0.370 | Biomarker | disease | BEFREE | The triggering receptor expressed by myeloid cells-1 activates TLR4-MyD88-NF-κB-dependent signaling to aggravate ventilation-induced lung inflammation and injury in mice. | 29869715 | 2018 | ||||
|
0.370 | Biomarker | disease | BEFREE | In order to understand how the absence of MyD88 can interfere in the laser effect on lung inflammation, MyD88<sup>-/-</sup> mice were treated or not with laser and subjected to occlusion of the superior mesenteric artery (45 min) followed by intestinal reperfusion (4 h). | 27924419 | 2017 | ||||
|
0.370 | Biomarker | disease | BEFREE | The results showed an alleviated pulmonary inflammation and fibrosis in myeloid differentiation primary response gene 88 (MyD88)-deficient mice treated with bleomycin (BLM), accompanied with a reduced TGF-β signaling and production of pro-fibrotic cytokines, including TNF-α, IL-1β. | 28662409 | 2017 | ||||
|
0.370 | Biomarker | disease | BEFREE | HMGB1 translocation and release mediate cigarette smoke-induced pulmonary inflammation in mice through a TLR4/MyD88-dependent signaling pathway. | 27807045 | 2017 | ||||
|
0.370 | Biomarker | disease | CTD_human | Desert dust induces TLR signaling to trigger Th2-dominant lung allergic inflammation via a MyD88-dependent signaling pathway. | 26882889 | 2016 | ||||
|
0.370 | Biomarker | disease | BEFREE | We conclude that MyD88-dependent signaling through multiple receptors is important in the pathogenesis of acute lung inflammation and injury following ischemia and reperfusion. | 24146959 | 2013 | ||||
|
0.370 | Biomarker | disease | BEFREE | Caveolin-1 Tyr14 phosphorylation induces interaction with TLR4 in endothelial cells and mediates MyD88-dependent signaling and sepsis-induced lung inflammation. | 24244013 | 2013 |