Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.060 AlteredExpression phenotype BEFREE Increased expression of STAT3 in human nonmelanoma skin cancer (NMSC) has been confirmed in a few studies, but to our knowledge, expression of STAT5A, STAT5B and STAT6 in BCC has not been previously evaluated. 31323143 2020
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.060 Biomarker phenotype BEFREE Previously, we reported that Stat3-coordinated Lin-28B-let-7-HMGA2 axis initiated EMT in BCCs. 30917918 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.060 AlteredExpression phenotype BEFREE One of the cytokines suggested to be involved in the pathogenesis of BCC is IL-6, which is the upstream element of IL-6/JAK/STAT3 pathway. 31342143 2019
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.060 PosttranslationalModification phenotype BEFREE In order to evaluate the possible effects of STAT3 phosphorylation and expression of E-cadherin on metastasis of some human epidermal non-melanoma cutaneous tumors, the expression of phosphorylated STAT3 (p-STAT3) and E-cadherin were analyzed by immunohistochemistry staining in formalin-fixed, paraffin-embedded tissue sections of human cutaneous squamous cell carcinoma (SCC), basal cell carcinoma (BCC) and seborrhoeic keratosis (SK). 16043897 2005
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.060 Biomarker phenotype BEFREE Interleukin-6 induced basic fibroblast growth factor-dependent angiogenesis in basal cell carcinoma cell line via JAK/STAT3 and PI3-kinase/Akt pathways. 15610530 2004
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.060 Biomarker phenotype BEFREE Unexpectedly, without ultraviolet B irradiation, STAT3F transfection also induced a significant apoptosis in basal cell carcinoma/interleukin-6 cells. 12445202 2002