Gene: VDR ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7421
Gene Symbol: VDR
VDR 		0.060 GeneticVariation phenotype BEFREE Our findings support the hypothesis that inherited common variation in VDR binding sites affects the development of BCC. 28177523 2017
Entrez Id: 7421
Gene Symbol: VDR
VDR 		0.060 GeneticVariation phenotype BEFREE The vitamin D endocrine system is implicated in skin carcinogenesis and polymorphisms in genes associated with the vitamin D receptor (VDR) gene may alter the risk of keratinocyte cancers (basal cell carcinoma (BCC) and squamous cell carcinoma (SCC)). 27127116 2016
Entrez Id: 7421
Gene Symbol: VDR
VDR 		0.060 AlteredExpression phenotype BEFREE Finally, analysis of samples from patients with squamous cell carcinoma (SCC), basal cell carcinoma and precursors to invasive SCC demonstrated a significant correlation between p63 and VDR levels when compared with healthy normal skin control samples. 26068789 2015
Entrez Id: 7421
Gene Symbol: VDR
VDR 		0.060 Biomarker phenotype BEFREE The hedgehog pathway gene SNPs studied, along with the VDR and FAS SNPs studied, are not strongly associated with the BCC cancer-prone phenotype. 22677152 2012
Entrez Id: 7421
Gene Symbol: VDR
VDR 		0.060 AlteredExpression phenotype BEFREE The expression of the VDR and MTHFR proteins was significantly higher in BCCs of the patients than in the healthy skin of the controls. 21732987 2011
Entrez Id: 7421
Gene Symbol: VDR
VDR 		0.060 GeneticVariation phenotype BEFREE We determined whether the multiple cluster MPP was associated with characteristics associated with sensitivity to UV or glutathione S-transferase (GST) GSTT1, GSTM1, cytochrome P450 (CYP) CYP2D6, tumour necrosis factor (TNF)-alpha and vitamin D receptor (VDR) genotypes previously associated with BCC presentational phenotypes. 11337940 2001