Gene: LRRK2 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2 		0.030 GeneticVariation disease BEFREE LRRK2 pathophysiology remains unclear, but reduced dopamine and mitochondrial abnormalities occur in aged G2019S mutant knock-in (GKI) mice. 28930069 2017
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2 		0.030 GeneticVariation disease BEFREE Mitochondrial abnormalities are a common feature in PD pathogenesis and we have investigated the impact of G2019S mutant LRRK2 expression on mitochondrial bioenergetics. 22736029 2012
Entrez Id: 120892
Gene Symbol: LRRK2
LRRK2 		0.030 GeneticVariation disease BEFREE In addition, we observe autophagic and mitochondrial abnormalities in the brains of aged G2019S LRRK2 mice and markedly reduced neurite complexity of cultured dopaminergic neurons. 21494637 2011