| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | Biomarker | disease | BEFREE | Significant independent predictors for disease-free survival were age (p = 0.015), MEN2 (p = 0.002), pre-op calcitonin (p = 0.033) and venous invasion (p = 0.001). | 29484475 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | The patient has a pentagastrin-induced rise in serum calcitonin (up to 57 pg/ml) considered normal for noncarriers but abnormal in family members of MEN-2 patients. | 16356097 | 2005 | ||||
|
0.080 | Biomarker | disease | BEFREE | Medullary thyroid carcinoma (MTC) is a malignant tumor of the calcitonin-secreting parafollicular C cells of the thyroid occurring sporadically and as a component of the multiple endocrine neoplasia type 2/familial medullary thyroid carcinoma syndrome. | 12679485 | 2003 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | We conclude that routine basal serum calcitonin measurement in nodular thyroid disease and thoughtful use of ret-mutation analysis is cost-effective in detecting medullary thyroid carcinoma and multiple endocrine neoplasia type II. | 10474127 | 1999 | ||||
|
0.080 | Biomarker | disease | BEFREE | This investigation deals with the potential additional value of serum CGRP measurements as compared to calcitonin in screening for medullary carcinoma of the thyroid (MTC) in families with multiple endocrine neoplasia type 2 (MEN 2). | 2574082 | 1989 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | However, neither calcitonin nor CGRP mRNA was detected in a pheochromocytoma from 1 of the patients who had multiple endocrine neoplasia type II. | 3485648 | 1986 | ||||
|
0.080 | Biomarker | disease | BEFREE | The authors measured plasma calcitonin and plasma catecholamines in 21 members of a family with Sipple syndrome. | 7267504 | 1981 | ||||
|
0.080 | Biomarker | disease | BEFREE | Serum carcinoembryonic antigen (CEA) and calcitonin were assayed in 8 patients with medullary carcinoma of the thyroid (MCT) and 14 unaffected family members, from 4 pedigrees of Sipple's syndrome and one pedigree with inherited MCT. | 476574 | 1979 |