| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | GeneticVariation | disease | BEFREE | Our study aimed to evaluate the association between IL-1α (4845 G/T), IL-1β (-511C/T) and IL-1RN (VNTR) polymorphisms and risk of cervical cancer. | 25925136 | 2015 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Fourteen studies testing the association between IL-1β and/or IL-1RN gene polymorphisms and cervical cancer were examined: 5 studies of IL-1β-511C/T, 3 studies of IL-1β-31T/C, and 6 studies of IL-1RN. | 24905619 | 2014 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | The meta-analysis suggests that the CTLA-4 +49 A/G and IL-1B -511 C/T polymorphisms are associated with cervical cancer in East Asians, and that the IL-1RN VNTR polymorphism is associated with cervical cancer in Indians. | 24712845 | 2014 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Our results indicated that IL-1RN A2 allele is associated with an increased susceptibility to cervical cancer development, probably by increasing predisposition to shorter immune responses. | 23053980 | 2012 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | In a case-control study we analyzed the polymorphism of IL-1RA in 150 women with cervical cancer and 209 healthy controls. | 18008080 | 2008 | ||||
|
0.090 | Biomarker | disease | BEFREE | Haplotype IL-1RN*2/IL-1beta*T is associated with higher risk and of cervical cancer. | 18333945 | 2008 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Patients with a heterozygosity of allele 2 for IL-1 RA (IL-RA1/2) have an increased risk of cervical cancer. | 12530098 | 2003 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | In a prospective study we analysed the polymorphism of IL-1RA in 113 women with cervical cancer and 107 with benign diseases. | 12820354 | 2003 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | Several human ovarian and cervical cancer cell lines spontaneously express the icIL-1Ra. icIL-1Ra-expressing cells did not have altered growth characteristics or altered short term responses to IL-1 compared with icIL-1Ra-nonexpressing cells. | 7594609 | 1995 |