Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 367
Gene Symbol: AR
AR 		0.500 GeneticVariation disease BEFREE The CAG and GGC repeats in the AR have been studied extensively as markers of prostate cancer susceptibility, with inconclusive findings, whereas the AR-E211 G>A polymorphism has been associated with androgenetic alopecia. 15824176 2005
Entrez Id: 367
Gene Symbol: AR
AR 		0.500 GeneticVariation disease BEFREE The ubiquity of the androgen receptor gene StuI restriction site, and higher incidence of shorter triplet repeat haplotypes in bald men suggests that these markers are very close to a functional variant that is a necessary component of the polygenic determination of male pattern baldness. 11231320 2001
Entrez Id: 367
Gene Symbol: AR
AR 		0.500 GeneticVariation disease BEFREE Androgen receptor polymorphisms (CAG repeat lengths) in androgenetic alopecia, hirsutism, and acne. 9677254 1998
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2 		0.410 GeneticVariation disease GWASCAT Detection and interpretation of shared genetic influences on 42 human traits. 27182965 2016
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2 		0.410 Biomarker disease CTD_human 5alpha-Reductase type 2 gene variant associations with prostate cancer risk, circulating hormone levels and androgenetic alopecia. 17136762 2007
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2 		0.410 GeneticVariation disease BEFREE The purpose of our study is to investigate the genetic polymorphisms of steroid 5alpha-reductase type 1 and 2 (SRD5A1 and SRD5A2) genes in Korean population, and to study the association of these polymorphisms with the development, clinical types (female or male pattern) and therapeutic response of androgenetic alopecia. 12670724 2003
Entrez Id: 387
Gene Symbol: RHOA
RHOA 		0.300 Biomarker disease CTD_human Postzygotic inactivating mutations of RHOA cause a mosaic neuroectodermal syndrome. 31570889 2019
Entrez Id: 5573
Gene Symbol: PRKAR1A
PRKAR1A 		0.300 Biomarker disease CTD_human PKA signaling drives reticularis differentiation and sexually dimorphic adrenal cortex renewal. 29367455 2018
Entrez Id: 23476
Gene Symbol: BRD4
BRD4 		0.300 Biomarker disease CTD_human Inducible in vivo silencing of Brd4 identifies potential toxicities of sustained BET protein inhibition. 25242322 2014
Entrez Id: 7421
Gene Symbol: VDR
VDR 		0.300 Biomarker disease CTD_human Hairless modulates ligand-dependent activation of the vitamin D receptor-retinoid X receptor heterodimer. 22466564 2012
Entrez Id: 1392
Gene Symbol: CRH
CRH 		0.300 Biomarker disease CTD_human CRF receptor antagonist astressin-B reverses and prevents alopecia in CRF over-expressing mice. 21359208 2011
Entrez Id: 142
Gene Symbol: PARP1
PARP1 		0.300 Biomarker disease CTD_human Inflammatory and age-related pathologies in mice with ectopic expression of human PARP-1. 20561897 2010
Entrez Id: 54503
Gene Symbol: ZDHHC13
ZDHHC13 		0.300 Biomarker disease CTD_human Mice with alopecia, osteoporosis, and systemic amyloidosis due to mutation in Zdhhc13, a gene coding for palmitoyl acyltransferase. 20548961 2010
Entrez Id: 6832
Gene Symbol: SUPV3L1
SUPV3L1 		0.300 Biomarker disease CTD_human Disruption of Supv3L1 damages the skin and causes sarcopenia, loss of fat, and death. 19145458 2009
Entrez Id: 8797
Gene Symbol: TNFRSF10A
TNFRSF10A 		0.300 Biomarker disease CTD_human Mapatumumab, an antibody targeting TRAIL-R1, in combination with paclitaxel and carboplatin in patients with advanced solid malignancies: results of a phase I and pharmacokinetic study. 19652058 2009
Entrez Id: 1244
Gene Symbol: ABCC2
ABCC2 		0.300 Biomarker disease CTD_human Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis. 18381794 2008
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.300 Biomarker disease CTD_human Methotrexate (MTX) pathway gene polymorphisms and their effects on MTX toxicity in Caucasian and African American patients with rheumatoid arthritis. 18381794 2008
Entrez Id: 55806
Gene Symbol: HR
HR 		0.300 Biomarker disease CTD_human A novel missense mutation in the mouse hairless gene causes irreversible hair loss: genetic and molecular analyses of Hr m1Enu. 16455232 2006
Entrez Id: 7538
Gene Symbol: ZFP36
ZFP36 		0.300 Biomarker disease CTD_human Structure/function analysis of tristetraprolin (TTP): p38 stress-activated protein kinase and lipopolysaccharide stimulation do not alter TTP function. 15944294 2005
Entrez Id: 7421
Gene Symbol: VDR
VDR 		0.300 Biomarker disease CTD_human [Vitamin D-resistant rickets type II: apropos of 2 cases]. 1338926 1992
Entrez Id: 60401
Gene Symbol: EDA2R
EDA2R 		0.120 GeneticVariation disease BEFREE Investigation of the male pattern baldness major genetic susceptibility loci AR/EDA2R and 20p11 in female pattern hair loss. 22309448 2012
Entrez Id: 60401
Gene Symbol: EDA2R
EDA2R 		0.120 GeneticVariation disease GWASDB Six novel susceptibility Loci for early-onset androgenetic alopecia and their unexpected association with common diseases. 22693459 2012
Entrez Id: 60401
Gene Symbol: EDA2R
EDA2R 		0.120 Biomarker disease BEFREE EDA2R is associated with androgenetic alopecia. 18385763 2008
Entrez Id: 9734
Gene Symbol: HDAC9
HDAC9 		0.110 GeneticVariation disease GWASCAT GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk. 29146897 2017
Entrez Id: 2250
Gene Symbol: FGF5
FGF5 		0.110 GeneticVariation disease GWASCAT GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk. 29146897 2017