Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
0.070 Biomarker disease BEFREE The in vitro cell growth inhibitory activity of compounds <b>5</b>, <b>6</b>, <b>7</b>, <b>9</b>, and <b>10</b> was investigated in six human tumor cell lines: A375-C5 (malignant melanoma IL-1 insensitive), MCF-7 (breast adenocarcinoma), NCI-H460 (non-small cell lung cancer), U251 (glioblastoma astrocytoma), U373 (glioblastoma astrocytoma), and U87MG (glioblastoma astrocytoma). 29734739 2018
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
0.070 AlteredExpression disease BEFREE Previous studies reported on interleukin-1beta (IL-1beta) production and IL-1 receptor type I (IL-1RI, signaling receptor) expression in human astrocytomas, and on IL-1beta action in astrocytoma cell lines. 10654577 2000
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
0.070 Biomarker disease BEFREE We, therefore, examined the expression of IL-6, GM-CSF, and TNF-alpha in human primary astrocytes and astrocytoma cell lines U251 and 253 exposed to IL-1 in serum-free medium. 8903854 1995
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
0.070 AlteredExpression disease BEFREE In particular, an astrocytoma cell line U373MG subclone responded markedly to IL-1 with high expression levels of IL-8 and MCAF mRNA as well as IL-6 mRNA. 1937574 1991
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
0.070 AlteredExpression disease BEFREE IL1 induces proliferation and IL6 mRNA expression in a human astrocytoma cell line: positive and negative modulation by chorela toxin and cAMP. 2157429 1990
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
0.070 Biomarker disease BEFREE BSF-2/IL-6, GM-CSF and IL-1 beta mRNAs were induced by recombinant IL-1 in human astrocytoma cell line U373MG. 2646146 1989
Entrez Id: 3552
Gene Symbol: IL1A
IL1A
0.070 Biomarker disease BEFREE In this report we describe a human astrocytoma cell line (T24) which produces IL-1 constitutively and upon induction with phorbol myristate acetate in vitro. 2783391 1989