Gene: MGMT ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4255
Gene Symbol: MGMT
MGMT 		0.070 PosttranslationalModification disease BEFREE Long-term daily temozolomide with dose-dependent efficacy in MGMT promotor methylation negative recurrent high-grade astrocytoma. 28791452 2017
Entrez Id: 4255
Gene Symbol: MGMT
MGMT 		0.070 PosttranslationalModification disease BEFREE The aim of the present study is to clarify the significance of ATRX loss and its correlation with p53 overexpression, IDH1/2 mutations, 1p/19q-codeletion and MGMT hypermethylation in supertentorial astrocytoma, and to determine the prognostic value of these factors in Chinese patients. 26395639 2016
Entrez Id: 4255
Gene Symbol: MGMT
MGMT 		0.070 PosttranslationalModification disease BEFREE SATB1 expression was also significantly lower in astrocytoma specimens with MGMT promoter methylation than in those without MGMT promoter methylation. 23317753 2013
Entrez Id: 4255
Gene Symbol: MGMT
MGMT 		0.070 PosttranslationalModification disease BEFREE MGMT promoter hypermethylation is a frequent, early, and consistent event in astrocytoma progression, and not correlated with TP53 mutation. 20593220 2011
Entrez Id: 4255
Gene Symbol: MGMT
MGMT 		0.070 PosttranslationalModification disease BEFREE MGMT activity, promoter methylation and immunohistochemistry of pretreatment and recurrent malignant gliomas: a comparative study on astrocytoma and glioblastoma. 20131314 2010
Entrez Id: 4255
Gene Symbol: MGMT
MGMT 		0.070 Biomarker disease BEFREE The promoters of the RASSF1A (3p21.3), BLU (3p21.3) and MGMT (10q26) genes were analyzed by MCA-MSP and MCA-Meth in 13 astrocytoma samples, 6 high grade glioma cell lines and 4 neuroblastoma cell lines. 18298842 2008
Entrez Id: 4255
Gene Symbol: MGMT
MGMT 		0.070 PosttranslationalModification disease BEFREE Our findings suggest that p14(ARF) hypermethylation and MGMT hypermethylation constitute distinct molecular pathways of astrocytoma progression, which could differ in biological behavior and clinical outcome. 17493032 2007