| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.100 | AlteredExpression | disease | BEFREE | Four neuroblastoma cell lines were examined for their expression of IGF-II and IGF-receptor. | 12553057 | 2003 | ||||
|
0.100 | AlteredExpression | disease | BEFREE | The current study examines the effect of IGF-IR expression and activation on apoptosis in SHEP human neuroblastoma cells. | 10889510 | 2000 | ||||
|
0.100 | Biomarker | disease | BEFREE | In the present work, we studied the effect of insulin-like growth factor-1 (IGF-1) on 1-methyl-4-phenylpyridinium (MPP+)-induced apoptosis in human neuroblastoma SH-EP1 cells. | 20963499 | 2010 | ||||
|
0.100 | Biomarker | disease | BEFREE | Expression of the repressor element-1 silencing transcription factor (REST) is influenced by insulin-like growth factor-I in differentiating human neuroblastoma cells. | 15654842 | 2005 | ||||
|
0.100 | AlteredExpression | disease | BEFREE | Quantitative phosphoproteomic analysis identifies activation of the RET and IGF-1R/IR signaling pathways in neuroblastoma. | 24349301 | 2013 | ||||
|
0.100 | Biomarker | disease | BEFREE | Bcl-2 and M-Myc coexpression increases IGF-IR and features of malignant growth in neuroblastoma cell lines. | 11571630 | 2001 | ||||
|
0.100 | AlteredExpression | disease | BEFREE | Topotecan blocks hypoxia-inducible factor-1alpha and vascular endothelial growth factor expression induced by insulin-like growth factor-I in neuroblastoma cells. | 15930297 | 2005 | ||||
|
0.100 | AlteredExpression | disease | BEFREE | Nuclear estrogen receptor activation by insulin-like growth factor-1 in Neuro-2A neuroblastoma cells requires endogenous estrogen synthesis and is mediated by mutually repressive MAPK and PI3K cascades. | 30986444 | 2019 | ||||
|
0.100 | Biomarker | disease | BEFREE | Furthermore, the IGF-1 receptor antagonist NVP-AEW541 exaggerated cytolysis in children with OMS and NB. | 30718793 | 2019 | ||||
|
0.100 | Biomarker | disease | BEFREE | Our results provide the first evidence of a direct link between them and demonstrate the effects of the oncogene on components of the IGF system in neuroblastoma cell growth in vitro and in vivo. | 10383152 | 1999 |