Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8842
Gene Symbol: PROM1
PROM1
0.080 Biomarker disease BEFREE This study was performed to determine whether MYCN and CD133+ CSCs are associated with chemotherapy resistance and the survival time of patients with NB. 29322842 2018
Entrez Id: 8842
Gene Symbol: PROM1
PROM1
0.080 Biomarker disease BEFREE In this study, we showed that the surface marker CD133 method was more suitable for isolating NB CSCs than the side-population method, and 60 µM etoposide was optimal for enriching NB CSCs. 24789807 2014
Entrez Id: 8842
Gene Symbol: PROM1
PROM1
0.080 AlteredExpression disease BEFREE There was a significant association between CD133 expression and the following poor prognosis covariates: age, International Neuroblastoma Staging System stage, MYCN amplification, and phospho-AKT (pAKT) expression. 22394107 2012
Entrez Id: 8842
Gene Symbol: PROM1
PROM1
0.080 AlteredExpression disease BEFREE These abnormalities were found in NB samples and some were significantly correlated with CD133 expression. 22514116 2012
Entrez Id: 8842
Gene Symbol: PROM1
PROM1
0.080 Biomarker disease BEFREE Inhibition of the sonic hedgehog pathway by cyplopamine reduces the CD133+/CD15+ cell compartment and the in vitro tumorigenic capability of neuroblastoma cells. 21803487 2011
Entrez Id: 8842
Gene Symbol: PROM1
PROM1
0.080 Biomarker disease BEFREE A microarray time course analysis of serial spheres passages from metastatic cells allowed us to specifically "profile" the NB stem cell-like phenotype and to identify CD133, ABC transporter, and WNT and NOTCH genes as spheres markers. 22028624 2011
Entrez Id: 8842
Gene Symbol: PROM1
PROM1
0.080 PosttranslationalModification disease BEFREE Analysis of stemness gene expression and CD133 abnormal methylation in neuroblastoma cell lines. 20878131 2010
Entrez Id: 8842
Gene Symbol: PROM1
PROM1
0.080 Biomarker disease BEFREE Using side population (SP) cells as a marker for SLCC in human nasopharyngeal carcinoma (NPC) and CD133 for human neuroblastoma cells, we found that DNA damage inducers, UV and mitomycin C were capable of increasing SP cells in NPC CNE-2 and neuroblastoma SKN-SH cells. 20007324 2010