| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | GeneticVariation | disease | BEFREE | Preoperative metabolic tumor volume of intrahepatic cholangiocarcinoma measured by <sup>18</sup>F-FDG-PET is associated with the KRAS mutation status and prognosis. | 29642912 | 2018 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Molecular studies showed one mucinous iCC with KRAS G12C mutation and no BRAF or IDH1/2 mutations. | 29698701 | 2018 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Utility of KRAS mutational analysis in the preoperative diagnosis of synchronous pancreatic cancer and intrahepatic cholangiocarcinoma: A case report. | 29390348 | 2017 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | KRAS and p53 mutations are associated with an aggressive disease prognosis while FGFR mutations may signify a relatively indolent disease course of intrahepatic cholangiocarcinoma. | 27658789 | 2016 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | These latest advancements along with known mutations in KRAS/BRAF/EGFR and 11q13 high-level amplification have contributed to a better understanding of the landscape of molecular alterations in iCCA. | 26405193 | 2016 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | Establishment of a patient-derived intrahepatic cholangiocarcinoma xenograft model with KRAS mutation. | 26868125 | 2016 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | KRAS (P=0.0075) or GNAS mutations (P=0.0256) were associated with poor overall survival in all patients with intrahepatic cholangiocarcinoma. | 24186137 | 2014 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | In this study, we analyze a large set of intrahepatic cholangiocarcinoma tumors (n = 54) for mutations in these genes and compare the clinical outcomes of wild type versus KRAS and BRAF mutant cases. | 24139215 | 2013 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | The present results demonstrated a higher participation of Ki-ras gene mutations in EHC than found in previous studies, and provided a confirmation and extension of the results earlier reported by Tada et al. and Tsuda et al. for IHC. | 7830335 | 1994 |