Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2629
Gene Symbol: GBA
GBA
0.090 GeneticVariation disease BEFREE β-Glucocerebrosidase gene mutations in two cohorts of Greek patients with sporadic Parkinson's disease. 21745757 2012
Entrez Id: 2629
Gene Symbol: GBA
GBA
0.090 GeneticVariation disease BEFREE About one-third of patients with sporadic Parkinson disease (PD) and more than 40% of patients with familial PD of Ashkenazi Jewish descent likely carry the G2019S mutation in the LRRK2 gene, a mutation in the glucocerebrosidase (GBA) gene, or both. 25347348 2014
Entrez Id: 2629
Gene Symbol: GBA
GBA
0.090 GeneticVariation disease BEFREE Association between GBA L444P mutation and sporadic Parkinson's disease from Mainland China. 20004703 2010
Entrez Id: 2629
Gene Symbol: GBA
GBA
0.090 Biomarker disease BEFREE Characterization of Brain Lysosomal Activities in GBA-Related and Sporadic Parkinson's Disease and Dementia with Lewy Bodies. 29948939 2019
Entrez Id: 2629
Gene Symbol: GBA
GBA
0.090 GeneticVariation disease BEFREE Haploinsufficiency of the GBA gene, leading to a reduction in glucocerebrosidase (GCase) activity, is one of the most common genetic risk factors for PD. 29735433 2018
Entrez Id: 2629
Gene Symbol: GBA
GBA
0.090 GeneticVariation disease BEFREE Mutations in the LRRK2 and GBA genes are increasingly recognized as frequent determinants of familial and sporadic Parkinson's disease (PD). 23726462 2013
Entrez Id: 2629
Gene Symbol: GBA
GBA
0.090 GeneticVariation disease BEFREE Parkin levels were slightly increased only in the PD group without GBA1 mutations and were not significantly modified by ambroxol. 26094596 2015
Entrez Id: 2629
Gene Symbol: GBA
GBA
0.090 Biomarker disease BEFREE The characteristic clinical phenotype of GBA1-PD resembles sporadic Parkinson disease, but with an earlier onset and more severe course. 31188151 2019
Entrez Id: 2629
Gene Symbol: GBA
GBA
0.090 GeneticVariation disease BEFREE We investigated relationships between Parkinson's disease-specific glucocerebrosidase deficits, glucocerebrosidase-related pathways, and α-synuclein levels in brain tissue from subjects with sporadic Parkinson's disease without GBA1 mutations. 24477431 2014