Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7001
Gene Symbol: PRDX2
PRDX2
0.030 AlteredExpression disease BEFREE Overexpression of peroxiredoxin 2 and VEGFR2 in pterygium might be involved in the pathogenesis or recurrence of pterygium. 28489720 2017
Entrez Id: 7001
Gene Symbol: PRDX2
PRDX2
0.030 AlteredExpression disease BEFREE Among these genes, we chose three proteins, aldehyde dehydrogenase, dimeric NADP-preferring (ALDH3A1), protein disulfide-isomerase A3 (PDIA3), and peroxiredoxin-2 (PRDX2), that were significantly upregulated in pterygium and further increased in recurrent pterygium. 25221425 2014
Entrez Id: 7001
Gene Symbol: PRDX2
PRDX2
0.030 Biomarker disease BEFREE Although, these results suggest that overexpression of peroxiredoxin 2 in pterygium could protect the cell against oxidative stress-induced apoptosis, further studies are required to establish the functional role of peroxiredoxin 2 in pterygium to determine its role in peroxidation and apoptosis in this pathology. 23499777 2013