Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
0.030 Biomarker disease BEFREE Here, we discuss the roles of PGC1s in healthy liver and explore their contribution to the pathogenesis and future therapy of NASH and HCC. 30518830 2019
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
0.030 Biomarker disease BEFREE The protein levels of peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α), mitofusin-2 (Mfn-2) and OXPHOS complexes (human: COI and COIII; cow: COI-IV) were significantly decreased in patients and cows with NASH. 29602237 2018
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
0.030 GeneticVariation disease BEFREE Further, there was an additive effect of the PPARGC1A rs8192678 GA/AA genotype and the PNPLA3 rs738409 GG genotype on the presence of NASH (OR 6.83; 95% CI 1.61-29.01; P = 0.009).The PPARGC1A rs8192678 GA/AA genotype and the PNPLA3 rs738409 GG genotype had an additive effect on NASH in severely obese Taiwanese patients. 27015186 2016