Gene: INTU ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 27152
Gene Symbol: INTU
INTU 		0.030 Biomarker disease BEFREE INT-767 was given by gavage to NASH rats from week 13 to week 16. 30038487 2018
Entrez Id: 27152
Gene Symbol: INTU
INTU 		0.030 GeneticVariation disease BEFREE In a proof-of-concept study, <i>Lep<sup>ob/ob</sup></i> (<i>ob/ob</i>) NASH mice were first dosed with INT-767 (3 or 10 mg/kg for 8 wk). 29375205 2018
Entrez Id: 27152
Gene Symbol: INTU
INTU 		0.030 Biomarker disease BEFREE Obeticholic acid (<b>INT-747</b>), a FXR agonist, has advanced into clinical phase III trials in patients with nonalcoholic steatohepatitis (NASH), but adverse effects (e.g., pruritus, LDL increase) were observed. 29259742 2017