Gene: APOE ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.100 Biomarker disease BEFREE The model shows that, for instance, APOE carriers have a significantly higher pace of cortical atrophy but not earlier atrophy onset. 29780348 2018
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.100 GeneticVariation disease BEFREE Healthy versus Entorhinal Cortical Atrophy Identification in Asymptomatic APOE4 Carriers at Risk for Alzheimer's Disease. 29278888 2018
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.100 Biomarker disease BEFREE We identified the prevalence of APOE-ε4 and evaluated its association with cortical atrophy. 30511009 2018
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.100 Biomarker disease BEFREE As the detrimental effects of APOE4 seen in older AD patients were not found in younger AD patients, we suggest that some unrevealed factors are associated with cortical atrophy and non-amnestic cognitive dysfunction in young AD with APOE4 noncarriers. 29376853 2018
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.100 Biomarker disease BEFREE Higher CAIDE Dementia Risk Score (version without APOE) was significantly associated with higher total tau, more severe MTA, WMC, and global cortical atrophy-frontal subscale. 27143429 2016
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.100 Biomarker disease BEFREE Compared to HC, APOE ε 4 carriers presented cortical atrophy in right cingulate gyrus (R_CG) (GMV: APOE carriers: 8475.23 ± 1940.73 mm3, HC: 9727.34 ± 1311.57 mm3, t = 2.314, p = 0.026, corrected) and left insular (GMT: APOE ε 4 carriers: 3.83 ± 0.37 mm, HC: 4.05 ± 0.25 mm, t = 2.197, p = 0.033, corrected). 27097839 2016
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.100 Biomarker disease BEFREE Asymmetry of cortical atrophy and normal APOE ε4 prevalence constitute deviations from typical AD. 27566743 2016
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.100 GeneticVariation disease BEFREE In conclusion, in our sample CI was associated with higher subcortical damage and cortical atrophy but not with APOE-epsilon4 genotype. 19965518 2009
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.100 GeneticVariation disease BEFREE Our aim was to define the relationship between APOE epsilon4 allele load and regionally-specific brain cortical atrophy in Alzheimer's Disease (AD). 19013250 2009
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.100 Biomarker disease BEFREE Here we aimed to identify APOE-related patterns of cortical atrophy in AD using an advanced computational anatomy technique. 19349226 2009
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.100 Biomarker disease BEFREE These findings indicate that, in the age range of this cohort, ApoE-4 effects on cortical atrophy and cognitive performances of healthy elderly are limited to epsilon(4) homozygous subjects. 15670698 2005
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.100 GeneticVariation disease BEFREE The Apolipoprotein E genotype in patients affected by syndromes with focal cortical atrophy. 11311499 2001