Gene: MDH2 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4191
Gene Symbol: MDH2
MDH2 		0.150 GeneticVariation disease BEFREE Role of MDH2 pathogenic variant in pheochromocytoma and paraganglioma patients. 30008476 2018
Entrez Id: 4191
Gene Symbol: MDH2
MDH2 		0.150 Biomarker disease BEFREE ACC = adrenal cortical carcinoma; APA = aldosterone-producing adenoma; APCC = aldosterone-producing cell cluster; CAH = congenital adrenal hyperplasia; CT = computed tomography; DOTATATE = [<sup>68</sup>Ga]-DOTA(0)-Tyr(3)-octreotate; FDG = fluorodeoxyglucose; FH = fumarate hydratase; MR = miner-alocorticoid; MDH2 = malate dehydrogenase 2; PCC = pheochromocytoma; PET = positron emission tomography; PGL = paraganglioma; SCS = subclinical cortisol-secreting; SDHB = succinate dehydrogenase subunit B; TCGA = The Cancer Genome Atlas. 28332880 2017
Entrez Id: 4191
Gene Symbol: MDH2
MDH2 		0.150 Biomarker disease BEFREE Disruption of the Krebs cycle is a hallmark of cancer, and MDH2 has been recently identified as a novel pheochromocytoma and paraganglioma susceptibility gene. 27989324 2017
Entrez Id: 4191
Gene Symbol: MDH2
MDH2 		0.150 GeneticVariation disease BEFREE Cluster 1 mutations are involved with the pseudo hypoxic pathway and comprised of PHD2, VHL, SDHx, IDH, HIF2A, MDH2 and FH mutated PCC/PGL. 26839173 2016
Entrez Id: 4191
Gene Symbol: MDH2
MDH2 		0.150 Biomarker disease BEFREE Segregation of the mutation with disease and absence of MDH2 in mutated tumors revealed MDH2 as a novel pheochromocytoma/paraganglioma susceptibility gene. 25766404 2015
Entrez Id: 4191
Gene Symbol: MDH2
MDH2 		0.150 Biomarker disease HPO