Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 727837
Gene Symbol: SSX2B
SSX2B
0.100 GeneticVariation group BEFREE We attempted to determine the influence of the two alternative forms of the SYT-SSX fusion gene on tumor morphology and clinical outcome in patients with this sarcoma. 9428816 1998
Entrez Id: 727837
Gene Symbol: SSX2B
SSX2B
0.100 Biomarker group BEFREE A KRAB-related domain and a novel transcription repression domain in proteins encoded by SSX genes that are disrupted in human sarcomas. 9788446 1998
Entrez Id: 727837
Gene Symbol: SSX2B
SSX2B
0.100 AlteredExpression group BEFREE In three types of SSs, monophasic fibrous, biphasic and poorly differentiated, NBT/BCIP signals corresponding to SYT-SSX mRNA were uniformly and predominantly positive in the sarcoma cell cytoplasm. 16142418 2005
Entrez Id: 727837
Gene Symbol: SSX2B
SSX2B
0.100 GeneticVariation group BEFREE A characteristic SYT-SSX fusion gene resulting from the chromosomal translocation t(X;18)(p11;q11) is detectable in almost all synovial sarcomas, a malignant soft tissue tumor widely believed to originate from as yet unidentified pluripotent stem cells. 19936258 2009
Entrez Id: 727837
Gene Symbol: SSX2B
SSX2B
0.100 Biomarker group BEFREE Furthermore, tumors were screened for gene fusions (PAX3-FKHR, ASPL-TFE3, and SYT-SSX) previously shown to be associated with MET activation in sarcomas. 20512480 2010
Entrez Id: 727837
Gene Symbol: SSX2B
SSX2B
0.100 Biomarker group BEFREE SYT-SSX is thought to be responsible for sarcoma initiation and development. 22594313 2012
Entrez Id: 727837
Gene Symbol: SSX2B
SSX2B
0.100 GeneticVariation group BEFREE Synovial sarcoma is a translocation-associated sarcoma where the underlying chromosomal event generates SS18-SSX fusion transcripts. 22439931 2012
Entrez Id: 727837
Gene Symbol: SSX2B
SSX2B
0.100 GeneticVariation group BEFREE Synovial sarcoma (SS) is a malignant soft tissue tumor harboring chromosomal translocation t(X; 18)(p11.2; q11.2), which produces SS-specific fusion gene, SYT-SSX. 23313505 2013
Entrez Id: 727837
Gene Symbol: SSX2B
SSX2B
0.100 GeneticVariation group BEFREE As one of the first sarcomas to be defined by the presence of a specific chromosomal translocation leading to the production of the SS18-SSX fusion oncogene, it is perhaps the archetypal "translocation-associated sarcoma," and its translocation remains unique to this tumor type. 25438927 2014
Entrez Id: 727837
Gene Symbol: SSX2B
SSX2B
0.100 Biomarker group BEFREE SYT-SSX is considered to be responsible for sarcoma initiation and progression. 28498445 2017