Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.100 GeneticVariation group BEFREE The DNA sequence of CTNNB1 exon 3 in the desmoid-type fibromatosis and the subsequent postradiation sarcoma was determined. 26414222 2015
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.100 Biomarker group BEFREE Thus, cyclin D1 could be considered as one of the targets of the nuclear beta-catenin in spindle cell and pleomorphic sarcomas. 16733209 2006
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.100 AlteredExpression group BEFREE Furthermore, the expression of beta-catenin, an important component of the Wnt-signalling pathway, was regulated in an opposite manner to SFRP4, being particularly increased in undifferentiated sarcomas. 15307134 2004
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.100 GeneticVariation group BEFREE A pathological review and a molecular analysis (CTNNB1 gene mutation) were performed (National re-reading network of sarcomas-RRePS). 31016642 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.100 Biomarker group BEFREE Nuclear beta-catenin immunoreactivity was detected in 11 low-grade endometrial stromal sarcomas (92%) and 6 undifferentiated endometrial sarcomas (75%). 18376386 2008
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.100 Biomarker group BEFREE A total of 69 LSTs, comprising 36 Gr-LSTs and 33 NGr-LSTs, were immunohistochemically stained with MUC2, MUC5AC, MUC6, CD10 (markers of gastrointestinal cell lineage), p53, β-catenin and Ki-67 antibodies, and examined for alteration in exon 1 of v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) and exon 15 of v-raf murine sarcoma viral oncogene homologue B1 (BRAF) by polymerase chain reaction followed by direct sequencing. 23112547 2012
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.100 AlteredExpression group BEFREE We investigated the genetic alterations of the CTNNB1 coding beta-catenin protein and expression of several genes downstream of Wnt signals in 4 benign and 17 malignant pediatric liver tumors (PLTs) consisting of 15 HBL, 1 hepatocellular carcinoma, and 1 hepatic immature sarcoma. 16465411 2006
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.100 Biomarker group BEFREE Beta-catenin was identified with intracytoplasmic and nuclear accumulation, showing additional membranous staining in sarcomas with epithelioid pattern. 11007041 2000
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.100 Biomarker group BEFREE The findings of the present study support the notion that Wnt/β‑catenin activation may serve a differential role in sarcomas, limiting tumor progression in association with decreased CSC activity. 31180539 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.100 Biomarker group BEFREE Signaling through the WNT/β-catenin and the RAS (rat sarcoma)/MAPK (mitogen-activated protein kinase) pathways plays a key role in the regulation of various physiological cellular processes including proliferation, differentiation, and cell death. 23483189 2013
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.100 GeneticVariation group BEFREE Biphenotypic sinonasal sarcoma: A series of six cases with evaluation of role of β-catenin immunohistochemistry in differential diagnosis. 29566950 2018
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
0.100 AlteredExpression group BEFREE Immunohistochemistry revealed overexpression of cyclin D1 in 2 out of 8 endometrial stromal nodules, 1 out of 17 low-grade endometrial stromal sarcomas, and 6 out of 13 undifferentiated endometrial sarcomas, and these 6 undifferentiated endometrial sarcomas simultaneously expressed nuclear beta-catenin. 19898427 2010