Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 23152
Gene Symbol: CIC
CIC
0.100 Biomarker group BEFREE The diagnosis of sarcoma with CIC-DUX4 gene fusion is difficult in lack of specific pathological characteristics emphasizing the need for molecular analysis. 28466754 2019
Entrez Id: 23152
Gene Symbol: CIC
CIC
0.100 Biomarker group BEFREE Heterogeneous elements included a myxoid spindle cell component in three BCOR-CCNB3 sarcomas and an epithelioid cell component in two CIC-associated sarcomas (one CIC-DUX4-positive and one CIC-DUX4-negative sarcomas). 28197724 2017
Entrez Id: 23152
Gene Symbol: CIC
CIC
0.100 GeneticVariation group BEFREE A recently characterized group of undifferentiated small round cell sarcomas harbours fusions of the genes CIC and DUX4. 27790742 2017
Entrez Id: 23152
Gene Symbol: CIC
CIC
0.100 Biomarker group BEFREE The CIC-DUX4 sarcoma is a small round blue cell sarcoma which presents like extraskeletal Ewing sarcoma, but is negative for the EWSR1 gene translocation. 30353686 2018
Entrez Id: 23152
Gene Symbol: CIC
CIC
0.100 GeneticVariation group BEFREE Primitive round- or spindle-cell EWSR1-negative undifferentiated sarcomas harboring CIC-DUX4 gene fusion are the most common form of Ewing-like sarcomas. 28474974 2019
Entrez Id: 23152
Gene Symbol: CIC
CIC
0.100 Biomarker group BEFREE Herein, we describe the clinicopathologic features and comprehensive molecular profiling of 4 cases of primary renal CIC-rearranged sarcomas. 29901569 2018
Entrez Id: 23152
Gene Symbol: CIC
CIC
0.100 Biomarker group BEFREE Aside from the desmoplastic stroma, the CIC-FOXO4 fusion sarcoma showed morphologic and immunohistochemical similarity to ESFT and Ewing-like sarcomas, including the recently described CIC-DUX4 fusion sarcoma. 25007147 2014
Entrez Id: 23152
Gene Symbol: CIC
CIC
0.100 GeneticVariation group BEFREE Ewing sarcoma is the prototype of round cell sarcoma whereas in CIC sarcomas, focal pleomorphism and epithelioid morphology can predominate. 31802230 2020
Entrez Id: 23152
Gene Symbol: CIC
CIC
0.100 Biomarker group BEFREE Unsupervised clustering by RNAseq data revealed that tumors with BCOR genetic alterations, including BCOR-CCNB3, BCOR-MAML3, and BCOR ITD, formed a tight genomic group distinct from ES and CIC-rearranged sarcomas. 29300189 2018
Entrez Id: 23152
Gene Symbol: CIC
CIC
0.100 Biomarker group BEFREE CIC-DUX4 sarcoma represents a novel translocation-associated sarcoma with distinctive histopathologic features and rapid disease progression. 23887164 2013
Entrez Id: 23152
Gene Symbol: CIC
CIC
0.100 AlteredExpression group BEFREE We performed a detailed immunohistochemical analysis to investigate ETV4 expression in CIC-rearranged undifferentiated round-cell sarcomas and their potential mimics (especially Ewing sarcomas). 27562494 2016