Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2078
Gene Symbol: ERG
ERG
0.070 AlteredExpression group BEFREE In nine cases of CIC-associated sarcoma, CD56 was expressed in five, alpha-smooth muscle actin in one, ERG in three, and CD99, WT1 and TLE1 each in eight cases. 28197724 2017
Entrez Id: 2078
Gene Symbol: ERG
ERG
0.070 GeneticVariation group BEFREE NKX2-2 was positive in 37/40 (93%) Ewing sarcomas, including all atypical Ewing sarcomas and cases with known EWSR1-FLI1 or EWSR1-ERG fusion; 85% of Ewing sarcomas showed diffuse (>50%) staining. 26847175 2016
Entrez Id: 2078
Gene Symbol: ERG
ERG
0.070 Biomarker group BEFREE All 3 CIC-rearranged AS cases lacked vasoformation and had a solid growth of round, epithelioid to rhabdoid cells, showing immunoreactivity for CD31 and Ets-related gene and sharing a transcriptional signature with other round cell sarcomas, including CIC-rearranged tumors. 26735859 2016
Entrez Id: 2078
Gene Symbol: ERG
ERG
0.070 Biomarker group BEFREE In conclusion, strong nuclear ERG immunoreactivity is specific for Ewing sarcomas with EWSR1-ERG rearrangement. 22766791 2012
Entrez Id: 2078
Gene Symbol: ERG
ERG
0.070 AlteredExpression group BEFREE ERG (Ets related gene) overexpression or increased activity has been found in various human cancers, including sarcomas, acute myeloid leukemia and prostate cancer, where the ERG gene is rearranged due to chromosomal translocations. 20814243 2010
Entrez Id: 2078
Gene Symbol: ERG
ERG
0.070 GeneticVariation group BEFREE The EWS-ERG fusion protein is found in human sarcomas with the chromosomal translocation t(21;22)(q22;q12), where the translocation is considered to be an initiating event in sarcoma formation within uncommitted mesenchymal cells, probably long-lived progenitors capable of self renewal. 15974803 2005
Entrez Id: 2078
Gene Symbol: ERG
ERG
0.070 GeneticVariation group BEFREE Translocation of the ERG gene t(21;22) results in the chimeric fusion transcript seen in approximately 10% of Ewings sarcomas. 7731694 1995