Significant correlations between pyruvate-to-lactate rate constants and <sup>18</sup>F-FDG uptake were found for sarcoma patients, whereas no significant correlations appeared for carcinoma patients.
This work arises from consideration of sarcoma patients in which fluorodeoxyglucose positron emission tomography (FDG-PET) imaging pre-therapy and post-chemotherapy is used to assess treatment response.