Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
0.100 Biomarker group BEFREE BCOR-CCNB3 sarcomas showed swirling fascicular growth. 31647130 2020
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
0.100 Biomarker group BEFREE Fine-Needle Aspiration Features of BCOR-CCNB3 Sarcoma. 31679010 2020
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
0.100 Biomarker group BEFREE The tumor showed an undifferentiated phenotype, including negativity for cytokeratin, although it was immunoreactive to BCOR and MUC4, and was initially suspected as BCOR-associated sarcoma. 31385070 2020
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
0.100 Biomarker group BEFREE BCOR sarcomas often exhibit a spindled neoplastic cell population. 31802230 2020
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
0.100 GeneticVariation group BEFREE Accumulating evidence suggests that internal tandem duplications (ITD) of BCOR are oncogenic drivers in a subset of pediatric sarcomas and rare adult tumors. 30380541 2019
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
0.100 Biomarker group BEFREE The BCOR-CCNB3 positive sarcoma is a recently identified sarcoma morphologically and clinically similar to Ewing sarcoma in adolescents and young adults. 30064235 2019
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
0.100 GeneticVariation group BEFREE These include gene fusions in vascular neoplasms (FOSB, CAMTA1 and TFE3), round cell sarcomas (BCOR, DUX4 and WT1), and fibroblastic/myofibroblastic tumors (STAT6, ALK and Pan-TRK); amplifications in well-differentiated and dedifferentiated liposarcomas (MDM2 and CDK4); and deletions in several aggressive neoplasms (SMARCB1 and SMARCA4). 30382607 2019
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
0.100 Biomarker group BEFREE RNA-sequencing data identified one <i>BCOR-CCNB3</i> gene fusion-positive sarcoma occurring in the sacrum of a 17-year-old male patient. 31632552 2019
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
0.100 Biomarker group BEFREE More than 50% of cases stained positive for SATB2 and Pax8, raising the hypothesis of a potential use of these markers in the identification of BCOR-CCNB3 positive undifferentiated/unclassified sarcomas. 28420319 2019
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
0.100 Biomarker group BEFREE BCOR-CCNB3 fusion sarcoma is cyclin B3-positive, usually occurs in bone or soft tissue of children, and may mimic a poorly differentiated synovial sarcoma. 30633925 2019
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
0.100 Biomarker group BEFREE BCOR genetic abnormalities have been found in some Ewing-like sarcomas. 31702654 2019
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
0.100 Biomarker group BEFREE BCOR ITD were present in 1 uterine sarcoma diagnosed as HG-ESS and 2 undifferentiated sarcomas with uniform nuclear features, all of which lacked any of the recurrent chromosome translocations known to occur in ESS. 29200103 2018
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
0.100 GeneticVariation group BEFREE Unsupervised clustering by RNAseq data revealed that tumors with BCOR genetic alterations, including BCOR-CCNB3, BCOR-MAML3, and BCOR ITD, formed a tight genomic group distinct from ES and CIC-rearranged sarcomas. 29300189 2018
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
0.100 GeneticVariation group BEFREE NKX2.2, ETV4 and BCOR immunoreactivity was observed in all ES, CIC-rearranged sarcomas and sarcomas with BCOR alteration, respectively. 29661713 2018
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
0.100 Biomarker group BEFREE We herein focus on novel immunohistochemical markers, based on molecular genetic alterations, which are particularly useful in the diagnostic workup of selected groups of soft tissue and bone tumors, including recently described entities, specifically round cell sarcomas (Ewing sarcoma, CIC-rearranged sarcoma, and BCOR-rearranged sarcoma), vascular tumors (epithelioid hemangioma, epithelioid hemangioendothelioma, and pseudomyogenic hemangioendothelioma), SMARCB1-deficient neoplasms, adipocytic tumors (spindle cell/pleomorphic lipoma, atypical spindle cell lipomatous tumor, and conventional atypical lipomatous tumor), giant cell-rich bone tumors (giant cell tumor of bone and chondroblastoma), and biphenotypic sinonasal sarcoma. 30134255 2018
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
0.100 GeneticVariation group BEFREE We discuss the spectrum of these tumors, from the benign endometrial stromal nodule to low-grade endometrial stromal sarcoma to uterine undifferentiated sarcomas with a special emphasis on the expanding group of high-grade stromal sarcomas, recently added to the 2014 WHO classification, not only discussing the well-established YWHAE-FAM22 tumors but also two new groups, presenting with BCOR alterations including those with BCOR tandem internal duplications or NTRK fusions. 30324234 2018
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
0.100 Biomarker group BEFREE These results are in keeping with a "BCOR-alteration family" of renal and extrarenal neoplasms which includes CCSK and undifferentiated round cell sarcomas of soft tissue/primitive myxoid mesenchymal tumor of infancy (which typically harbor BCOR internal tandem duplication), and BCOR-CCNB3 sarcomas, all of which are primarily driven by BCOR overexpression and have overlapping (but not identical) clinicopathologic features. 28817404 2017
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
0.100 Biomarker group BEFREE A new group of sarcomas with a recurrent BCOR-CCNB3 gene fusion has been recently identified in previously unclassifiable small round cell sarcomas. 28756981 2017
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
0.100 Biomarker group BEFREE Heterogeneous elements included a myxoid spindle cell component in three BCOR-CCNB3 sarcomas and an epithelioid cell component in two CIC-associated sarcomas (one CIC-DUX4-positive and one CIC-DUX4-negative sarcomas). 28197724 2017
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
0.100 Biomarker group BEFREE The spectrum of ELS is now expanding, and additional gene fusion partners besides DUX4 or CCNB3 have been detected, and the terms CIC or BCOR-rearranged sarcomas have recently been proposed. 27306060 2016
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
0.100 Biomarker group BEFREE Nonetheless, NKX2-2 may be helpful to distinguish Ewing sarcoma from some histologic mimics including CIC-DUX4 and BCOR-CCNB3 sarcomas. 26847175 2016
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
0.100 GeneticVariation group BEFREE In addition, we included related pathologic entities such as 8 CCSKs and other sarcomas with BCOR gene fusions. 27428733 2016
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
0.100 Biomarker group BEFREE Sarcomas harbouring BCOR-CCNB3 rarely arise from soft tissues; therefore, we aimed to report four cases to expand the clinicopathological spectrum. 27228320 2016
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
0.100 Biomarker group BEFREE In the control cohort, BCOR ITD was found only in 3 CCSK cases but not in the other sarcomas. 26945340 2016
Entrez Id: 54880
Gene Symbol: BCOR
BCOR
0.100 Biomarker group BEFREE Novel BCOR-MAML3 and ZC3H7B-BCOR Gene Fusions in Undifferentiated Small Blue Round Cell Sarcomas. 26752546 2016