Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6857
Gene Symbol: SYT1
SYT1
0.100 Biomarker group BEFREE SYT-SSX is considered to be responsible for sarcoma initiation and progression. 28498445 2017
Entrez Id: 6857
Gene Symbol: SYT1
SYT1
0.100 Biomarker group BEFREE A specific translocation in this sarcoma induces fusion of the SYT gene on chromosome 18 to the SSX genes on chromosome X, leading to proliferation of the tumor cells. 26250552 2015
Entrez Id: 6857
Gene Symbol: SYT1
SYT1
0.100 Biomarker group BEFREE SYT-SSX is thought to be responsible for sarcoma initiation and development. 22594313 2012
Entrez Id: 6857
Gene Symbol: SYT1
SYT1
0.100 Biomarker group BEFREE These results support the notion that the SYT-SSX2 nuclear function and differentiation effects are conserved throughout sarcoma development and are required for its maintenance beyond the initial phase. 21996728 2012
Entrez Id: 6857
Gene Symbol: SYT1
SYT1
0.100 Biomarker group BEFREE Furthermore, tumors were screened for gene fusions (PAX3-FKHR, ASPL-TFE3, and SYT-SSX) previously shown to be associated with MET activation in sarcomas. 20512480 2010
Entrez Id: 6857
Gene Symbol: SYT1
SYT1
0.100 GeneticVariation group BEFREE A characteristic SYT-SSX fusion gene resulting from the chromosomal translocation t(X;18)(p11;q11) is detectable in almost all synovial sarcomas, a malignant soft tissue tumor widely believed to originate from as yet unidentified pluripotent stem cells. 19936258 2009
Entrez Id: 6857
Gene Symbol: SYT1
SYT1
0.100 GeneticVariation group BEFREE Synovial sarcoma is a soft tissue cancer associated with a recurrent t(X:18) translocation event that generates one of two fusion proteins, SYT-SSX1 or SYT-SSX2. 19337376 2009
Entrez Id: 6857
Gene Symbol: SYT1
SYT1
0.100 GeneticVariation group BEFREE With this method, 27 tumors (9 synovial sarcomas and 18 nonsynovial sarcomas) were studied and showed SYT-SSX1 rearrangement in 6 cases and SYT-SSX2 in 3 cases. 15747098 2005
Entrez Id: 6857
Gene Symbol: SYT1
SYT1
0.100 AlteredExpression group BEFREE In three types of SSs, monophasic fibrous, biphasic and poorly differentiated, NBT/BCIP signals corresponding to SYT-SSX mRNA were uniformly and predominantly positive in the sarcoma cell cytoplasm. 16142418 2005
Entrez Id: 6857
Gene Symbol: SYT1
SYT1
0.100 GeneticVariation group BEFREE We attempted to determine the influence of the two alternative forms of the SYT-SSX fusion gene on tumor morphology and clinical outcome in patients with this sarcoma. 9428816 1998
Entrez Id: 6857
Gene Symbol: SYT1
SYT1
0.100 GeneticVariation group BEFREE Fifteen other sarcomas and related tumors were negative for SYT-SSX fusion transcripts. 9688183 1998