Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10021
Gene Symbol: HCN4
HCN4 		0.300 Biomarker disease CLINGEN Mutation in S6 domain of HCN4 channel in patient with suspected Brugada syndrome modifies channel function. 27553229 2016
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B 		0.300 Biomarker disease CLINGEN Embryonic type Na+ channel β-subunit, SCN3B masks the disease phenotype of Brugada syndrome. 27677334 2016
Entrez Id: 6327
Gene Symbol: SCN2B
SCN2B 		0.300 Biomarker disease CLINGEN Scn2b Deletion in Mice Results in Ventricular and Atrial Arrhythmias. 27932425 2016
Entrez Id: 3752
Gene Symbol: KCND3
KCND3 		0.300 Biomarker disease CLINGEN Two novel Brugada syndrome-associated mutations increase KV4.3 membrane expression and function. 26016905 2015
Entrez Id: 6327
Gene Symbol: SCN2B
SCN2B 		0.300 Biomarker disease CLINGEN Contribution of Cardiac Sodium Channel β-Subunit Variants to Brugada Syndrome. 26179811 2015
Entrez Id: 6327
Gene Symbol: SCN2B
SCN2B 		0.300 Biomarker disease CLINGEN Comprehensive Genetic Characterization of a Spanish Brugada Syndrome Cohort. 26173111 2015
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B 		0.300 Biomarker disease CLINGEN Contribution of Cardiac Sodium Channel β-Subunit Variants to Brugada Syndrome. 26179811 2015
Entrez Id: 5318
Gene Symbol: PKP2
PKP2 		0.300 Biomarker disease CLINGEN Epicardial Ventricular Tachycardia Ablation in a Patient With Brugada ECG Pattern and Mutation of PKP2 and DSP Genes. 25900994 2015
Entrez Id: 781
Gene Symbol: CACNA2D1
CACNA2D1 		0.300 Biomarker disease CLINGEN Functional characterization of CaVα2δ mutations associated with sudden cardiac death. 25527503 2015
Entrez Id: 5318
Gene Symbol: PKP2
PKP2 		0.300 Biomarker disease CLINGEN High prevalence of concealed Brugada syndrome in patients with atrioventricular nodal reentrant tachycardia. 25998140 2015
Entrez Id: 781
Gene Symbol: CACNA2D1
CACNA2D1 		0.300 Biomarker disease CLINGEN Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics. 24309898 2014
Entrez Id: 5318
Gene Symbol: PKP2
PKP2 		0.300 Biomarker disease CLINGEN Arrhythmogenic cardiomyopathy and provocable Brugada ECG in a patient caused by missense mutation in plakophilin-2. 24681023 2014
Entrez Id: 5318
Gene Symbol: PKP2
PKP2 		0.300 Biomarker disease CLINGEN Missense mutations in plakophilin-2 cause sodium current deficit and associate with a Brugada syndrome phenotype. 24352520 2014
Entrez Id: 5318
Gene Symbol: PKP2
PKP2 		0.300 Biomarker disease CLINGEN Desmosomes and the sodium channel complex: implications for arrhythmogenic cardiomyopathy and Brugada syndrome. 24656989 2014
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B 		0.300 Biomarker disease CLINGEN Is sudden unexplained nocturnal death syndrome in Southern China a cardiac sodium channel dysfunction disorder? 24529773 2014
Entrez Id: 3764
Gene Symbol: KCNJ8
KCNJ8 		0.300 Biomarker disease CLINGEN Role of ATP-sensitive K+ channels in cardiac arrhythmias. 24367007 2014
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B 		0.300 Biomarker disease CLINGEN Novel SCN3B mutation associated with brugada syndrome affects intracellular trafficking and function of Nav1.5. 23257389 2013
Entrez Id: 6327
Gene Symbol: SCN2B
SCN2B 		0.300 Biomarker disease CLINGEN A missense mutation in the sodium channel β2 subunit reveals SCN2B as a new candidate gene for Brugada syndrome. 23559163 2013
Entrez Id: 23493
Gene Symbol: HEY2
HEY2 		0.300 Biomarker disease CTD_human Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death. 23872634 2013
Entrez Id: 3752
Gene Symbol: KCND3
KCND3 		0.300 Biomarker disease CLINGEN Sodium current and potassium transient outward current genes in Brugada syndrome: screening and bioinformatics. 22284586 2012
Entrez Id: 783
Gene Symbol: CACNB2
CACNB2 		0.300 Biomarker disease CLINGEN Brugada-like syndrome in infancy presenting with rapid ventricular tachycardia and intraventricular conduction delay. 22090166 2012
Entrez Id: 783
Gene Symbol: CACNB2
CACNB2 		0.300 Biomarker disease CLINGEN Spectrum and prevalence of mutations involving BrS1- through BrS12-susceptibility genes in a cohort of unrelated patients referred for Brugada syndrome genetic testing: implications for genetic testing. 22840528 2012
Entrez Id: 3764
Gene Symbol: KCNJ8
KCNJ8 		0.300 Biomarker disease CLINGEN Molecular genetic and functional association of Brugada and early repolarization syndromes with S422L missense mutation in KCNJ8. 22056721 2012
Entrez Id: 5318
Gene Symbol: PKP2
PKP2 		0.300 Biomarker disease CLINGEN Sodium current deficit and arrhythmogenesis in a murine model of plakophilin-2 haploinsufficiency. 22764151 2012
Entrez Id: 3752
Gene Symbol: KCND3
KCND3 		0.300 Biomarker disease CLINGEN Spectrum and prevalence of mutations involving BrS1- through BrS12-susceptibility genes in a cohort of unrelated patients referred for Brugada syndrome genetic testing: implications for genetic testing. 22840528 2012