Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 21
Gene Symbol: ABCA3
ABCA3 		0.300 Biomarker disease CTD_human ABCA3 mutations led to pulmonary fibrosis and emphysema with pulmonary hypertension in an 8-year-old girl. 26780485 2016
Entrez Id: 59
Gene Symbol: ACTA2
ACTA2 		0.300 Biomarker disease CTD_human TMEM100 mediates inflammatory cytokines secretion in hepatic stellate cells and its mechanism research. 30639579 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ 		0.300 Therapeutic disease CTD_human Adiponectin attenuates lung fibroblasts activation and pulmonary fibrosis induced by paraquat. 25945502 2015
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.300 Therapeutic disease CTD_human Targeting the RAS axis alleviates silicotic fibrosis and Ang II-induced myofibroblast differentiation via inhibition of the hedgehog signaling pathway. 31181250 2019
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.300 Therapeutic disease CTD_human Angiotensin-(1-7)-mediated Mas1 receptor/NF-κB-p65 signaling is involved in a cigarette smoke-induced chronic obstructive pulmonary disease mouse model. 28960804 2018
Entrez Id: 374
Gene Symbol: AREG
AREG 		0.300 Biomarker disease CTD_human Self-assembled Micelle Interfering RNA for Effective and Safe Targeting of Dysregulated Genes in Pulmonary Fibrosis. 26817844 2016
Entrez Id: 655
Gene Symbol: BMP7
BMP7 		0.300 Therapeutic disease CTD_human Gremlin-mediated decrease in bone morphogenetic protein signaling promotes pulmonary fibrosis. 17975199 2008
Entrez Id: 796
Gene Symbol: CALCA
CALCA 		0.300 Biomarker disease CTD_human Calcitonin gene-related peptide (CGRP) as hazard marker for lung injury induced by dusts. 17365031 2007
Entrez Id: 847
Gene Symbol: CAT
CAT 		0.300 Therapeutic disease CTD_human Modulation of reactive oxygen species by Rac1 or catalase prevents asbestos-induced pulmonary fibrosis. 19684199 2009
Entrez Id: 6356
Gene Symbol: CCL11
CCL11 		0.300 Biomarker disease CTD_human Relationship between eosinophilia and levels of chemokines (CCL5 and CCL11) and IL-5 in bronchoalveolar lavage fluid of patients with mustard gas-induced pulmonary fibrosis. 17620002 2007
Entrez Id: 6356
Gene Symbol: CCL11
CCL11 		0.300 Biomarker disease CTD_human Role of Eotaxin-1 (CCL11) and CC chemokine receptor 3 (CCR3) in bleomycin-induced lung injury and fibrosis. 16314464 2005
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		0.300 Biomarker disease CTD_human Elevated levels of MCP-1, MIP-alpha and MIP-1 beta in the bronchoalveolar lavage (BAL) fluid of patients with mustard gas-induced pulmonary fibrosis. 17720292 2007
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		0.300 Biomarker disease CTD_human Role of human pulmonary fibroblast-derived MCP-1 in cell activation and migration in experimental silicosis. 26163174 2015
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		0.300 Biomarker disease CTD_human Gene expression of cytokines and growth factors in the lungs after paraquat administration in mice. 16324872 2006
Entrez Id: 6348
Gene Symbol: CCL3
CCL3 		0.300 Biomarker disease CTD_human Elevated levels of MCP-1, MIP-alpha and MIP-1 beta in the bronchoalveolar lavage (BAL) fluid of patients with mustard gas-induced pulmonary fibrosis. 17720292 2007
Entrez Id: 6348
Gene Symbol: CCL3
CCL3 		0.300 Biomarker disease CTD_human Gene expression of cytokines and growth factors in the lungs after paraquat administration in mice. 16324872 2006
Entrez Id: 6351
Gene Symbol: CCL4
CCL4 		0.300 Biomarker disease CTD_human Elevated levels of MCP-1, MIP-alpha and MIP-1 beta in the bronchoalveolar lavage (BAL) fluid of patients with mustard gas-induced pulmonary fibrosis. 17720292 2007
Entrez Id: 6352
Gene Symbol: CCL5
CCL5 		0.300 Biomarker disease CTD_human Relationship between eosinophilia and levels of chemokines (CCL5 and CCL11) and IL-5 in bronchoalveolar lavage fluid of patients with mustard gas-induced pulmonary fibrosis. 17620002 2007
Entrez Id: 1490
Gene Symbol: CCN2
CCN2 		0.300 Biomarker disease CTD_human Self-assembled Micelle Interfering RNA for Effective and Safe Targeting of Dysregulated Genes in Pulmonary Fibrosis. 26817844 2016
Entrez Id: 1490
Gene Symbol: CCN2
CCN2 		0.300 Biomarker disease CTD_human Simvastatin inhibits growth factor expression and modulates profibrogenic markers in lung fibroblasts. 15677772 2005
Entrez Id: 1490
Gene Symbol: CCN2
CCN2 		0.300 Biomarker disease CTD_human Connective tissue growth factor expression and induction by transforming growth factor-beta is abrogated by simvastatin via a Rho signaling mechanism. 15298857 2004
Entrez Id: 1490
Gene Symbol: CCN2
CCN2 		0.300 Biomarker disease CTD_human Connective tissue growth factor stimulates the proliferation, migration and differentiation of lung fibroblasts during paraquat-induced pulmonary fibrosis. 25815693 2015
Entrez Id: 729230
Gene Symbol: CCR2
CCR2 		0.300 Biomarker disease CTD_human CC-chemokine receptor 2 required for bleomycin-induced pulmonary fibrosis. 14609568 2003
Entrez Id: 1232
Gene Symbol: CCR3
CCR3 		0.300 Biomarker disease CTD_human Role of Eotaxin-1 (CCL11) and CC chemokine receptor 3 (CCR3) in bleomycin-induced lung injury and fibrosis. 16314464 2005
Entrez Id: 1050
Gene Symbol: CEBPA
CEBPA 		0.300 Therapeutic disease CTD_human Taurine ameliorates particulate matter-induced emphysema by switching on mitochondrial NADH dehydrogenase genes. 29078374 2017