Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 51091
Gene Symbol: SEPSECS
SEPSECS
0.080 Biomarker disease BEFREE Prospectively collected data from 89 anti-SLA/LP-positive AIH patients (29 from Hamburg-Germany, 20 from Bologna-Italy and 40 from Larissa-Greece) were analysed retrospectively. 31626725 2020
Entrez Id: 51091
Gene Symbol: SEPSECS
SEPSECS
0.080 Biomarker disease BEFREE Ag-specific stimulation of PBMC from AIH patients with the AIH-associated autoantigen SEPSECS resulted in significant TNF production only in patients manifesting SLA/LP autoantibodies targeting SEPSEC but not in healthy individuals who do not manifest this reactivity. 31685647 2019
Entrez Id: 51091
Gene Symbol: SEPSECS
SEPSECS
0.080 Biomarker disease BEFREE Total IgG was elevated, along with positive serology for anti-hepatitis A virus (HAV)-IgM, antinuclear antibodies (ANAs) and soluble liver antigen (SLA) leading to the differential diagnosis of acute hepatitis A and autoimmune hepatitis. 31079040 2019
Entrez Id: 51091
Gene Symbol: SEPSECS
SEPSECS
0.080 Biomarker disease BEFREE Type 3 (AIH) was solely characterized by the occurrence of soluble liver antigen/liver-pancreas antigen (SLA/LP) autoantibodies either with or without ANA or SMA autoantibodies. 17006990 2006
Entrez Id: 51091
Gene Symbol: SEPSECS
SEPSECS
0.080 Biomarker disease BEFREE Autoantibodies to soluble liver antigen and liver pancreas (SLA/LP) have been described as specific markers for Autoimmune Hepatitis (AIH), occurring in about 20% of patients with AIH. 11826415 2002
Entrez Id: 51091
Gene Symbol: SEPSECS
SEPSECS
0.080 Biomarker disease BEFREE Antibodies to a soluble liver antigen/liver pancreas (SLA/LP) appear to be highly specific for the diagnosis of autoimmune hepatitis. 11481605 2001
Entrez Id: 51091
Gene Symbol: SEPSECS
SEPSECS
0.080 Biomarker disease BEFREE Soluble liver antigen: isolation of a 35-kd recombinant protein (SLA-p35) specifically recognizing sera from patients with autoimmune hepatitis. 11230739 2001
Entrez Id: 51091
Gene Symbol: SEPSECS
SEPSECS
0.080 Biomarker disease BEFREE Autoantibodies to soluble liver antigen (SLA) and to liver and pancreas antigen (LP) have been described as disease specific, occurring in about 30% of all patients with autoimmune hepatitis, but no standardised assays are available. 10801173 2000