Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.500 Biomarker disease HPO
Entrez Id: 999
Gene Symbol: CDH1
CDH1
0.400 GeneticVariation disease UNIPROT
Entrez Id: 6794
Gene Symbol: STK11
STK11
0.360 GeneticVariation disease UNIPROT
Entrez Id: 22800
Gene Symbol: RRAS2
RRAS2
0.300 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.200 Biomarker disease HPO
Entrez Id: 11200
Gene Symbol: CHEK2
CHEK2
0.200 GeneticVariation disease CLINVAR
Entrez Id: 5728
Gene Symbol: PTEN
PTEN
0.200 Biomarker disease HPO
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.200 Biomarker disease HPO
Entrez Id: 79728
Gene Symbol: PALB2
PALB2
0.200 Biomarker disease HPO
Entrez Id: 675
Gene Symbol: BRCA2
BRCA2
0.200 Biomarker disease HPO
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.200 Biomarker disease HPO
Entrez Id: 672
Gene Symbol: BRCA1
BRCA1
0.200 GeneticVariation disease CLINVAR
Entrez Id: 5889
Gene Symbol: RAD51C
RAD51C
0.200 Biomarker disease HPO
Entrez Id: 4089
Gene Symbol: SMAD4
SMAD4
0.170 Biomarker disease HPO
Entrez Id: 5727
Gene Symbol: PTCH1
PTCH1
0.140 Biomarker disease HPO
Entrez Id: 8643
Gene Symbol: PTCH2
PTCH2
0.100 Biomarker disease HPO
Entrez Id: 23022
Gene Symbol: PALLD
PALLD
0.100 Biomarker disease HPO
Entrez Id: 51684
Gene Symbol: SUFU
SUFU
0.100 Biomarker disease HPO
Entrez Id: 104472848
Gene Symbol: IRAIN
IRAIN
0.010 Biomarker disease BEFREE <b>Aim:</b> To evaluate the potential of IGF1R as a prognostic marker for high-grade serous ovarian cancer (HGSOC) patients. 31140856 2019
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.100 AlteredExpression disease BEFREE <b>Conclusion</b>: Taken together, we demonstrated that EGF secreted by M2-like TAMs might suppress LIMT expression via activating EGFR-ERK signaling pathway to promote the progression of OC. 31062668 2019
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
0.080 Biomarker disease BEFREE <b>Conclusion:</b> IGF1R prognosticates prolonged survival in HGSOC patients, possibly due to its positive correlation with hCtr1. 31140856 2019
Entrez Id: 9342
Gene Symbol: SNAP29
SNAP29
0.010 Biomarker disease BEFREE <b>Conclusion:</b> Our findings suggest that down-regulation of OGT enhances cisplatin-induced autophagy via SNAP-29, resulting in cisplatin-resistant ovarian cancer. 30555541 2018
Entrez Id: 94025
Gene Symbol: MUC16
MUC16
0.100 Biomarker disease BEFREE <b>Conclusions.</b> Our study suggests that the CA125 nadir value is the most reliable prognostic factor to predict PFS and OS in advanced EOC patients treated with NAC. 29151924 2017
Entrez Id: 6935
Gene Symbol: ZEB1
ZEB1
0.100 Biomarker disease BEFREE <b>Conclusions:</b> As both Snail and ZEB1 are crucial inducers of epithelial-to-mesenchymal transition (EMT), our data suggested that CD44 may be crucial for the EMT process of ovarian cancer. 31497537 2019
Entrez Id: 960
Gene Symbol: CD44
CD44
0.100 Biomarker disease BEFREE <b>Conclusions:</b> As both Snail and ZEB1 are crucial inducers of epithelial-to-mesenchymal transition (EMT), our data suggested that CD44 may be crucial for the EMT process of ovarian cancer. 31497537 2019