Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.040 AlteredExpression disease BEFREE Basal cell carcinoma (BCC) has been genetically associated with an increased expression of angiotensin-converting enzyme (ACE), an important factor of the renin-angiotensin system which produces vasoconstrictor angiotensin II. 31570446 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.040 GeneticVariation disease BEFREE We systematically reviewed observational studies published through August 2016 and reported the KC risk (basal cell carcinoma [BCC] and squamous cell carcinoma [SCC]) associated with antihypertensive drugs, including diuretics, angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), beta-adrenergic blocking agents (β-blockers), and calcium channel blockers (CCBs). 29318704 2018
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.040 GeneticVariation disease BEFREE These findings indicate that the low expression ACE I allele carriers have a decreased risk for BCC. 23299466 2013
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.040 Biomarker disease BEFREE Additionally, ACE immunoreactivity was also significantly higher in BCC, compared with SCC (p < 0.05). 24203630 2013