Gene: KRAS ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.100 GeneticVariation disease BEFREE <i>Conclusions.</i> Although the number of patients analysed was limited, we found that the addition of cetuximab significantly improves the outcomes in KRAS wild type patients with unresectable colorectal cancer liver-confined metastases. 28167959 2017
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.100 GeneticVariation disease BEFREE (b) K-ras gene mutation can be identified in routinely obtained colonic washings of patients who are at risk of developing colorectal cancer. 8007010 1994
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.100 GeneticVariation disease BEFREE 2071 patients with colorectal cancer (1699 of Greek and 372 of Romanian origin) were analysed for KRAS exon 2 mutations. 24859998 2014
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.100 GeneticVariation disease BEFREE : The prognostic value of K-ras gene mutations was examined in patients with colorectal cancer who did not receive preoperative chemotherapy or radiation. 22810479 2012
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.100 GeneticVariation disease BEFREE Colorectal cancer-related mutant KRAS alleles function as positive regulators of autophagy. 26418750 2015
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.100 GeneticVariation disease BEFREE KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer. 16618717 2006
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.100 GeneticVariation disease BEFREE KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab. 18202412 2008
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.100 GeneticVariation disease BEFREE K-Ras mutations and treatment outcome in colorectal cancer patients receiving exclusive fluoropyrimidine therapy. 18676755 2008
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.100 Biomarker disease BEFREE KRAS mutational status as a predictor of epidermal growth factor receptor inhibitor efficacy in colorectal cancer. 19352138 2010
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.100 GeneticVariation disease BEFREE KRAS mutations and susceptibility to cetuximab and panitumumab in colorectal cancer. 19390304 2009
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.100 GeneticVariation disease BEFREE K-RAS mutation occurred in 36% (83/228) of our colorectal cancer cases. 19515263 2009
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.100 GeneticVariation disease BEFREE KRAS mutation testing in colorectal cancer. 19546608 2009
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.100 GeneticVariation disease BEFREE KRAS mutations have long been described to play an adverse prognostic role in colorectal cancer. 19632927 2009
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.100 GeneticVariation disease BEFREE KRAS mutations can be detected in approximately 30% to 40% of all patients with colorectal cancer. 19792050 2009
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.100 GeneticVariation disease BEFREE KRAS mutation and microsatellite instability: two genetic markers of early tumor development that influence the prognosis of colorectal cancer. 19813061 2010
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.100 GeneticVariation disease BEFREE KRAS and BRAF mutations in advanced colorectal cancer are associated with poor prognosis but do not preclude benefit from oxaliplatin or irinotecan: results from the MRC FOCUS trial. 19884549 2009
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.100 Biomarker disease BEFREE KRAS status in patients with colorectal cancer peritoneal carcinomatosis and its impact on outcome. 19952717 2010
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.100 Biomarker disease BEFREE KRAS genotyping of paraffin-embedded colorectal cancer tissue in routine diagnostics: comparison of methods and impact of histology. 20007841 2010
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.100 GeneticVariation disease BEFREE KRAS-mutation(+) colorectal cancer with intermediate-methylation epigenotype showed significantly worse prognosis. 20028768 2010
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.100 GeneticVariation disease BEFREE KRAS mutation screening in colorectal cancer: From paper to practice. 20100685 2010
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.100 GeneticVariation disease BEFREE KRAS mutations in Slovene patients with colorectal cancer: frequency, distribution and correlation with the response to treatment. 20372787 2010
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.100 Biomarker disease BEFREE KRAS testing and its importance in colorectal cancer. 20425075 2010
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.100 GeneticVariation disease BEFREE KRAS mutation testing in colorectal cancer raised fundamental biological, clinical and molecular pathological questions as it has become a standard application for predicting sensitivity for anti-EGFR antibody therapies. 20718705 2010
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.100 GeneticVariation disease BEFREE KRAS mutation detection and prognostic potential in sporadic colorectal cancer using high-resolution melting analysis. 20959826 2010
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.100 Biomarker disease BEFREE KRAS genotyping as biomarker in colorectal cancer: a comparison of three commercial kits on histologic material. 21187522 2010