Gene: PIK3CD ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 AlteredExpression disease BEFREE These data indicate that the capacity of retinol to inhibit PI3K activity confers its ability to decrease colorectal cancer metastasis. 25356626 2014
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE The role of c2orf68 and PI3K/Akt/mTOR pathway in human colorectal cancer. 25023051 2014
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE Expression of Ang-2/Tie-2 and PI3K/AKT in colorectal cancer. 25374184 2014
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE Our results suggest that knockdown of PI3K p85α is a potential therapeutic strategy in the treatment of colorectal cancer. 23990352 2013
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE We selected MAPK- and PI3K-pathway inhibition in colorectal cancer as a model system to dissect out mechanisms of resistance. 30905967 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE Arginine ADP-ribosyltransferase 1 promotes angiogenesis in colorectal cancer via the PI3K/Akt pathway. 26847718 2016
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 GeneticVariation disease BEFREE PI3K pathway activation occurs in concomitance with RAS/BRAF mutations in colorectal cancer, limiting the sensitivity to targeted therapies. 26272063 2015
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE DCLK1 promotes epithelial-mesenchymal transition via the PI3K/Akt/NF-κB pathway in colorectal cancer. 29277893 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE FAT4 regulates the EMT and autophagy in colorectal cancer cells in part via the PI3K-AKT signaling axis. 30832706 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE Tankyrase Inhibition Blocks Wnt/β-Catenin Pathway and Reverts Resistance to PI3K and AKT Inhibitors in the Treatment of Colorectal Cancer. 26224873 2016
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 AlteredExpression disease BEFREE NFkB is essential for activin-induced colorectal cancer migration via upregulation of PI3K-MDM2 pathway. 28418896 2017
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE Cudraflavone C Induces Tumor-Specific Apoptosis in Colorectal Cancer Cells through Inhibition of the Phosphoinositide 3-Kinase (PI3K)-AKT Pathway. 28107519 2017
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE Long non-coding RNA-SNHG7 acts as a target of miR-34a to increase GALNT7 level and regulate PI3K/Akt/mTOR pathway in colorectal cancer progression. 29970122 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE Further, the role of PI3K/Akt/mTOR inhibitors alone and in combination with other chemotherapeutic drugs, in alleviating colorectal cancer is also discussed. 31215384 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE EYA1 promotes tumor angiogenesis by activating the PI3K pathway in colorectal cancer. 29496520 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE Assessment of PI3K/AKT/PTEN signaling pathway activity in colorectal cancer using quantum dot-conjugated antibodies. 29422975 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE H19 regulates PI3K-Akt signal pathway through a competing endogenous RNA network and predicts poor prognosis in colorectal cancer. 31164794 2019
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 GeneticVariation disease BEFREE Concomitant BRAF and PI3K/mTOR blockade is required for effective treatment of BRAF(V600E) colorectal cancer. 23549875 2013
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE Collectively, we conclude that overexpression of CHRNA7 negatively controls colorectal cancer LoVo cell invasion and metastasis via PI3K/Akt pathway activation and may serve as either a diagnostic marker or a therapeutic target for colorectal cancer metastasis. 26719016 2016
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 GeneticVariation disease BEFREE PI3K expression and PIK3CA mutations are related to colorectal cancer metastases. 22851869 2012
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE Crocin synergistically enhances the antiproliferative activity of 5-flurouracil through Wnt/PI3K pathway in a mouse model of colitis-associated colorectal cancer. 30129057 2018
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 AlteredExpression disease BEFREE TCF21 functions as a tumor suppressor in colorectal cancer through inactivation of PI3K/AKT signaling. 28352192 2017
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE Exclusive inhibition of PI3K/Akt/mTOR signaling is not sufficient to prevent PDGF-mediated effects on glycolysis and proliferation in colorectal cancer. 27626684 2016
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 Biomarker disease BEFREE Dual-Blocking of PI3K and mTOR Improves Chemotherapeutic Effects on SW620 Human Colorectal Cancer Stem Cells by Inducing Differentiation. 26955235 2016
Entrez Id: 5293
Gene Symbol: PIK3CD
PIK3CD 		0.100 GeneticVariation disease BEFREE Importantly, a PI3K SL gene signature containing the top hits of the SL genes identified in our meta-analysis robustly predicted overall patient survival in colorectal cancer, especially among patients with tumors with an activated PI3K pathway. 28087713 2016