| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | GeneticVariation | disease | BEFREE | Genetic associations between the miRNA polymorphisms miR-130b (rs373001), miR-200b (rs7549819), and miR-495 (rs2281611) and colorectal cancer susceptibility. | 31117970 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | MAGP2, a Component of Extracellular Matrix, Is Upregulated in Colorectal Cancer and Negatively Modulated by miR-200b-3p. | 31426719 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | The RT-PCR-based MRC risk score = (-0.1218 × miR-744) + (-3.7142 × miR-429) + (-2.2051 × miR-362) + (3.0564 × miR-200b) + (2.4997 × miR-191) + (-0.0065 × miR-30c2) + (2.2224 × miR-30b) + (-1.1162 × miR-33a).<b>Conclusions:</b> This novel MRC is superior to currently used clinicopathologic features, as well as National Comprehensive Cancer Network (NCCN) criteria, and works regardless of adjuvant chemotherapy status in identifying patients with high-risk stage II and III colorectal cancer. | 29514841 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | Moreover, animal experiment studies also confirmed a stimulating effect of exosomal miR-200b on colorectal cancer cell-derived xenografts. | 30119180 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | miR‑200b‑3p inhibits proliferation and induces apoptosis in colorectal cancer by targeting Wnt1. | 30015876 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | Disruption of the c-Myc/miR-200b-3p/PRDX2 regulatory loop enhances tumor metastasis and chemotherapeutic resistance in colorectal cancer. | 29258530 | 2017 | ||||
|
0.080 | Biomarker | disease | BEFREE | microRNA-200b and microRNA-200c promote colorectal cancer cell proliferation via targeting the reversion-inducing cysteine-rich protein with Kazal motifs. | 25826661 | 2015 | ||||
|
0.080 | Biomarker | disease | BEFREE | In this study, we revealed a role for miR-200b in colorectal cancer. | 24151081 | 2014 |