Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
0.070 AlteredExpression disease BEFREE Serum TLR2 and TLR4 levels in colorectal cancer and their association with systemic inflammatory markers, tumor characteristics, and disease outcome. 31132191 2019
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
0.070 Biomarker disease BEFREE Toll-like receptor 2 stimulation promotes colorectal cancer cell growth via PI3K/Akt and NF-κB signaling pathways. 29689497 2018
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
0.070 AlteredExpression disease BEFREE TLR2 and TLR4 polymorphisms influence mRNA and protein expression in colorectal cancer. 26167073 2015
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
0.070 GeneticVariation disease BEFREE TLR2+597CC homozygous had 5-fold decreased risk (odds ratio (OR)=0.21, 95% CI: 0.09-0.50, p<0.001) and TLR4 299Gly homozygous 3-fold increased risk of colorectal cancer (OR=3.30, 95% CI: 1.18-9.28, p=0.015). 22999059 2013
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
0.070 GeneticVariation disease BEFREE The aim of this study was to determine whether there was a correlation between polymorphisms of TLR4 (Asp299Gly; Thr399Ile) and TLR2 (Arg677Trp; Arg753Gln) genes and risk of colorectal cancer. 21625017 2011
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
0.070 Biomarker disease BEFREE We utilized the AOM-DSS model for colitis-associated colorectal cancer (CAC) in wild type (WT) and TLR2(-/-) mice. 20885960 2010
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
0.070 GeneticVariation disease BEFREE Microsatelite GT polymorphism in the toll-like receptor 2 is associated with colorectal cancer. 16879199 2006