Gene: PTEN ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.100 Biomarker disease BEFREE ORR was 0% and 6 m PFS was 11% (1/9), observed in a patient with triple-negative breast cancer and PTEN loss. 31277699 2019
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.100 Biomarker disease BEFREE Compared with PTEN wild-type TNBC cells, PTEN mutant-type TNBC cells showed a decreased response to simvastatin. 23973711 2013
Entrez Id: 5728
Gene Symbol: PTEN
PTEN 		0.100 AlteredExpression disease BEFREE The AKT inhibitor capivasertib has shown preclinical activity in TNBC models, and drug sensitivity has been associated with activation of PI3K or AKT and/or deletions of PTEN. 31841354 2020