Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
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0.070 | Biomarker | disease | BEFREE | The aim of the present study was to ascertain whether miR‑145‑5p could discriminate between pCR and no‑pCR in triple‑negative breast cancer patients that received a cisplatin/doxorubicin‑based neoadjuvant treatment. miR‑145‑5p expression was determined in breast tumors by quantitative RT‑PCR. | 31002371 | 2019 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | We recently reported that Pten-loss cooperates with low expression of microRNA-145 to induce aggressive TNBC-like lesions in mice. | 30704524 | 2019 | ||||
|
0.070 | Biomarker | disease | BEFREE | Together, MUC1 was a potential molecular target may help explain the role of lincRNA-ROR/miR-145 for invasion and metastasis in TNBC cell lines. | 29673594 | 2018 | ||||
|
0.070 | Biomarker | disease | BEFREE | Therefore, our results indicate that miR-145 acts as a tumor suppressor in TNBC, suggesting that the miR-145-cIAP1 axis might be a potential therapeutic target for TNBC. | 26733177 | 2016 | ||||
|
0.070 | Biomarker | disease | BEFREE | These results demonstrated that miR-145 has an inhibitory role in TNBC malignancy by targeting MMP11 and Rab27a, which might be potential therapeutic and diagnostic targets for TNBC. | 27364572 | 2016 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | We report for the first time an extremely high prevalence (73.9%) of TNBC in premenopausal women below 35 years of age and a significant altered expression of a panel of three specific oncogenic miRNAs- miR-21, miR-221, miR-210, and three tumor suppressor miRNAs- miR-195, miR-145 and Let-7a in both tissues and corresponding sera of TNBC patients when compared with triple positive breast cancer (TPBC) patients. | 27404381 | 2016 | ||||
|
0.070 | Biomarker | disease | BEFREE | lincRNA-RoR and miR-145 regulate invasion in triple-negative breast cancer via targeting ARF6. | 25253741 | 2015 |