Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8795
Gene Symbol: TNFRSF10B
TNFRSF10B
0.040 Biomarker disease BEFREE Apoptotic Resistance of Metastatic Tumor Cells in Triple Negative Breast Cancer: Roles of Death Receptor-5. 31244295 2019
Entrez Id: 8795
Gene Symbol: TNFRSF10B
TNFRSF10B
0.040 Biomarker disease BEFREE These results suggest that CaM could be a key regulator to mediate DR5-mediated apoptotic signaling, and suggests a potential strategy for using CaM antagonists to overcome drug resistance of TRAIL-based therapy for TRA-8 resistant TNBC. 29663486 2018
Entrez Id: 8795
Gene Symbol: TNFRSF10B
TNFRSF10B
0.040 AlteredExpression disease BEFREE ET and DOX enhanced the DR5 expression in TNBC cells, whereas non-topoisomerase inhibitors pifithrin-α (PIF) and dexamethasone (DEX) failed to do so. 28702823 2017
Entrez Id: 8795
Gene Symbol: TNFRSF10B
TNFRSF10B
0.040 Biomarker disease BEFREE These findings support DR5 as a promising vaccine target for controlling TNBC and other DR5-positive cancers. 22419388 2012