| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | Biomarker | disease | BEFREE | Raine syndrome is characterized by FGF23-mediated hypophosphatemic osteomalacia with osteosclerosis caused by mutations in the FAM20C gene. | 30151622 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | Elevated FGF23 in a patient with hypophosphatemic osteomalacia associated with neurofibromatosis type 1. | 31476437 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | We report a case of a patient with Crohn's disease and chronic iron-deficiency anaemia receiving multiple doses of FCM who developed severe hypophosphataemic osteomalacia with urinary phosphate loss and increased FGF23. | 29298794 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | Here, we report an adult female who presented with hypophosphatemic osteomalacia and raised serum FGF23 concentrations. | 28982589 | 2018 | ||||
|
0.080 | Biomarker | disease | BEFREE | Iron-induced hypophosphataemic osteomalacia is thought to be due to reduced degradation of FGF23, resulting in phosphaturia and reduced synthesis of 1,25-dihydroxy vitamin D. Monitoring of patients on long-term parenteral iron is recommended to avoid clinically serious adverse effects. | 28203361 | 2017 | ||||
|
0.080 | Biomarker | disease | BEFREE | Tumor-induced osteomalacia (TIO) is a rare acquired form of hypophosphatemic osteomalacia, which is usually attributed to the overproduction of fibroblast growth factor 23 (FGF-23) by benign mesenchymal neoplasms. | 27085966 | 2017 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Our findings suggest that certain homozygous FAM20C mutations can cause FGF23-related hypophosphatemic osteomalacia and indicate the multiple roles of FAM20C in bone. | 24982027 | 2014 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | The expression level of FGF23 in isolated FD tissue with hypophosphatemic osteomalacia determined by real-time PCR was abundant close to the levels in OOM tumors. | 16337659 | 2006 |