Associated Disease N. genes N. variants N. of shared genes JI g p-value g N. of shared variants JI v p-value v
CUI: C0037773
Disease: Spastic Paraplegia, Hereditary
Spastic Paraplegia, Hereditary
123 41 67 0.34 8 6.3E-02
CUI: C0231687
Disease: Spastic gait
Spastic gait
62 9 42 0.26 2 2.0E-02
CUI: C0034935
Disease: Babinski Reflex
Babinski Reflex
218 11 71 0.24 1 9.7E-03
CUI: C0037771
Disease: Paraparesis, Spastic
Paraparesis, Spastic
75 37 33 0.18 3 2.4E-02
CUI: C1271100
Disease: Lower limb spasticity
Lower limb spasticity
43 0 28 0.18 0 0
CUI: C0034152
Disease: Henoch-Schoenlein Purpura
Henoch-Schoenlein Purpura
198 59 51 0.18 7 4.8E-02
CUI: C1836296
Disease: Muscle Weakness Lower Limb
Muscle Weakness Lower Limb
74 0 32 0.17 0 0
CUI: C0039273
Disease: Talipes cavus
Talipes cavus
213 0 43 0.14 0 0
Impaired vibration sensation in the lower limbs
39 0 22 0.14 0 0
CUI: C1855483
Disease: Progressive spastic paraplegia
Progressive spastic paraplegia
59 0 24 0.13 0 0
CUI: C1836696
Disease: Lower limb hyperreflexia
Lower limb hyperreflexia
38 6 21 0.13 1 1.0E-02
CUI: C0311394
Disease: Difficulty walking
Difficulty walking
224 0 40 0.12 0 0
CUI: C0238651
Disease: Ankle clonus
Ankle clonus
32 5 19 0.12 1 1.0E-02
Urinary bladder sphincter dysfunction
28 0 18 0.12 0 0
CUI: C0042024
Disease: Urinary Incontinence
Urinary Incontinence
151 0 30 0.11 0 0
CUI: C1848736
Disease: Distal amyotrophy
Distal amyotrophy
106 0 25 0.11 0 0
CUI: C0151889
Disease: Hyperreflexia
Hyperreflexia
539 19 67 0.11 1 9.0E-03
CUI: C1847584
Disease: Distal sensory impairment
Distal sensory impairment
86 0 22 0.11 0 0
Hereditary Autosomal Dominant Spastic Paraplegia
27 7 16 0.10 2 2.0E-02
CUI: C1263857
Disease: Peripheral axonal neuropathy
Peripheral axonal neuropathy
94 0 22 0.10 0 0
Autosomal Recessive Hereditary Spastic Paraplegia
20 0 15 0.10 0 0
CUI: C1854494
Disease: Slow progression
Slow progression
165 0 28 1.0E-01 0 0
CUI: C0085606
Disease: Urgency of micturition
Urgency of micturition
40 0 15 8.9E-02 0 0
CUI: C0575081
Disease: Gait abnormality
Gait abnormality
312 23 37 8.8E-02 2 1.8E-02
CUI: C0454596
Disease: Dysarthria, Spastic
Dysarthria, Spastic
30 0 14 8.7E-02 0 0