Disease: Microcephaly
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
DDX11 Q96FC9 DEAD/H-box helicase 11 Enzyme 2.3E-21 0.674 0.577
C2CD3 Q4AC94 C2 domain containing 3 centriole elongation regulator 4.4E-19 0.636 0.538
PMM2 O15305 phosphomannomutase 2 Enzyme 1.4E-17 0.535 0.769
POMT1 Q9Y6A1 protein O-mannosyltransferase 1 4.2E-17 0.525 0.615
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
CDK10 Q15131 cyclin dependent kinase 10 Kinase 1.2E-16 0.650 0.577
WWOX Q9NZC7 WW domain containing oxidoreductase Enzyme 1.2E-15 0.453 0.808
FANCM Q8IYD8 FA complementation group M Enzyme 2.4E-15 0.543 0.731
PRMT7 Q9NVM4 protein arginine methyltransferase 7 Epigenetic regulator 5.5E-15 0.674 0.538
ELN P15502 elastin 2.1E-14 0.415 0.885
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692
TELO2 Q9Y4R8 telomere maintenance 2 7.2E-14 0.695 0.500
FANCC Q00597 FA complementation group C 2.8E-13 0.507 0.808
PCDH12 Q9NPG4 protocadherin 12 2.9E-13 0.722 0.346
SMG9 Q9H0W8 SMG9 nonsense mediated mRNA decay factor 3.5E-13 0.729 0.346
DHCR7 Q9UBM7 7-dehydrocholesterol reductase Enzyme 3.9E-13 0.500 0.846
ACD Q96AP0 ACD shelterin complex subunit and telomerase recruitment factor 1.1E-12 0.603 0.731
TCTN3 Q6NUS6 tectonic family member 3 4.2E-12 0.566 0.615
POMT2 Q9UKY4 protein O-mannosyltransferase 2 9.4E-12 0.544 0.615
MASP1 P48740 mannan binding lectin serine peptidase 1 Enzyme 1.2E-11 0.565 0.885
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
TUBB3 Q13509 tubulin beta 3 class III Cellular structure 2.6E-10 0.486 0.808
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
RMDN1 Q96DB5 regulator of microtubule dynamics 1 5.9E-10 0.546 0.769