Disease: Cushing Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
AGRP O00253 agouti related neuropeptide Signaling 7.0E-04 0.488 0.769
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
AGTR1 P30556 angiotensin II receptor type 1 G-protein coupled receptor 5.3E-04 0.423 0.846
BRD2 P25440 bromodomain containing 2 Epigenetic regulator 1.00 0.450 0.808
CYP11B2 P19099 cytochrome P450 family 11 subfamily B member 2 7.1E-19 0.553 0.615
E2F1 Q01094 E2F transcription factor 1 Nucleic acid binding 0.99 0.441 0.846
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
GHRL Q9UBU3 ghrelin and obestatin prepropeptide 1.4E-11 0.517 0.769
GIP P09681 gastric inhibitory polypeptide 0.27 0.570 0.654
GIPR P48546 gastric inhibitory polypeptide receptor G-protein coupled receptor 2.0E-29 0.670 0.538
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
HSD11B1 P28845 hydroxysteroid 11-beta dehydrogenase 1 0.42 0.520 0.731
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
LEP P41159 leptin 0.46 0.349 0.846
MEN1 O00255 menin 1 1.00 0.444 0.808
NDRG2 Q9UN36 NDRG family member 2 Enzyme 2.2E-05 0.518 0.692
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PRKACB P22694 protein kinase cAMP-activated catalytic subunit beta Kinase 0.35 0.670 0.577
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
RET P07949 ret proto-oncogene Kinase 1.00 0.392 0.885