Disease: Pituitary-dependent Cushing's disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AGRP O00253 agouti related neuropeptide Signaling 7.0E-04 0.488 0.769
AIP O00170 aryl hydrocarbon receptor interacting protein Chaperone 0.36 0.517 0.769
ARHGAP24 Q8N264 Rho GTPase activating protein 24 3.9E-10 0.456 0.808
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BRD2 P25440 bromodomain containing 2 Epigenetic regulator 1.00 0.450 0.808
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
CIB1 Q99828 calcium and integrin binding 1 3.3E-04 0.458 0.769
E2F1 Q01094 E2F transcription factor 1 Nucleic acid binding 0.99 0.441 0.846
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
GHR P10912 growth hormone receptor Signaling 8.4E-05 0.490 0.846
GHRL Q9UBU3 ghrelin and obestatin prepropeptide 1.4E-11 0.517 0.769
GIP P09681 gastric inhibitory polypeptide 0.27 0.570 0.654
GNAI2 P04899 G protein subunit alpha i2 Enzyme modulator 0.89 0.636 0.577
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
H3P10 H3 histone pseudogene 10 0.350 0.846
HSD11B1 P28845 hydroxysteroid 11-beta dehydrogenase 1 0.42 0.520 0.731
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
MEN1 O00255 menin 1 1.00 0.444 0.808
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
POU1F1 P28069 POU class 1 homeobox 1 4.5E-02 0.548 0.654
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
PRKAR1A P10644 protein kinase cAMP-dependent type I regulatory subunit alpha 1.00 0.401 0.846
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885