Disease: Autoimmune thyroid disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AIRE O43918 autoimmune regulator 4.0E-12 0.516 0.808
CD226 Q15762 CD226 molecule 3.9E-02 0.548 0.769
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
CXCL10 P02778 C-X-C motif chemokine ligand 10 Signaling 0.37 0.378 0.885
FOXP3 Q9BZS1 forkhead box P3 0.99 0.368 0.846
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
HLA-DOA P06340 major histocompatibility complex, class II, DO alpha Immune response 3.0E-10 0.509 0.808
HLA-DPB1 P04440 major histocompatibility complex, class II, DP beta 1 Immune response 5.3E-10 0.453 0.923
HLA-DQA1 P01909 major histocompatibility complex, class II, DQ alpha 1 Immune response 2.4E-02 0.416 0.846
HLA-DQB1 P01920 major histocompatibility complex, class II, DQ beta 1 Immune response 8.9E-03 0.407 0.885
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
HT Hashimoto thyroiditis 0.505 0.731
IFIH1 Q9BYX4 interferon induced with helicase C domain 1 7.0E-44 0.471 0.808
IL15 P40933 interleukin 15 0.71 0.422 0.846
IL22 Q9GZX6 interleukin 22 1.9E-04 0.393 0.885
IL2RA P01589 interleukin 2 receptor subunit alpha Receptor 5.5E-02 0.389 0.885
IL6 P05231 interleukin 6 0.32 0.248 0.962
NUDT10 Q8NFP7 nudix hydrolase 10 Enzyme 0.11 0.705 0.423
NUDT11 Q96G61 nudix hydrolase 11 Enzyme 0.10 0.647 0.615
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846
RBM45 Q8IUH3 RNA binding motif protein 45 2.1E-10 0.383 0.846
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TPO P07202 thyroid peroxidase Enzyme 1.8E-21 0.455 0.846
VDR P11473 vitamin D receptor Nuclear receptor 1.7E-05 0.352 0.885