Disease: Multiple congenital anomalies
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
LEFTY2 O00292 left-right determination factor 2 Signaling 2.9E-04 0.736 0.231
PHF8 Q9UPP1 PHD finger protein 8 1.00 0.631 0.577
VRK1 Q99986 VRK serine/threonine kinase 1 Kinase 2.1E-03 0.621 0.615
RBM10 P98175 RNA binding motif protein 10 1.00 0.599 0.615
NRP2 O60462 neuropilin 2 8.1E-04 0.539 0.615
SOX2-OT SOX2 overlapping transcript 0.597 0.615
CDK13 Q14004 cyclin dependent kinase 13 Kinase 0.91 0.606 0.692
ALX4 Q9H161 ALX homeobox 4 0.36 0.560 0.692
CHUK O15111 component of inhibitor of nuclear factor kappa B kinase complex Kinase 0.99 0.556 0.731
ETV6 P41212 ETS variant transcription factor 6 Transcription factor 0.97 0.477 0.731
GPER1 Q99527 G protein-coupled estrogen receptor 1 G-protein coupled receptor 0.57 0.505 0.731
KCNH2 Q12809 potassium voltage-gated channel subfamily H member 2 Ion channel 1.00 0.522 0.731
PAX2 Q02962 paired box 2 0.67 0.495 0.731
PLCB4 Q15147 phospholipase C beta 4 Enzyme 3.0E-06 0.610 0.731
TRIO O75962 trio Rho guanine nucleotide exchange factor Kinase 1.00 0.556 0.731
BMP7 P18075 bone morphogenetic protein 7 Signaling 0.13 0.498 0.769
DDX3X O00571 DEAD-box helicase 3 X-linked 1.00 0.537 0.769
DVL1 O14640 dishevelled segment polarity protein 1 Signaling 3.7E-06 0.531 0.769
EFNB1 P98172 ephrin B1 Signaling 0.93 0.561 0.769
JAK1 P23458 Janus kinase 1 Kinase 1.00 0.474 0.769
MEF2C Q06413 myocyte enhancer factor 2C Transcription factor 1.7E-02 0.517 0.769
TFAP2A P05549 transcription factor AP-2 alpha Transcription factor 0.99 0.488 0.769
KDM6A O15550 lysine demethylase 6A Epigenetic regulator 1.00 0.498 0.769
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
SATB2 Q9UPW6 SATB homeobox 2 Transcription factor 1.00 0.503 0.769