Disease: Addison Disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CDKN1C P49918 cyclin dependent kinase inhibitor 1C 0.82 0.456 0.846
COX1 P00395 cytochrome c oxidase subunit I Enzyme 0.441 0.885
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
CYP11A1 P05108 cytochrome P450 family 11 subfamily A member 1 5.5E-07 0.547 0.731
CYP21A2 P08686 cytochrome P450 family 21 subfamily A member 2 2.6E-04 0.525 0.769
FOXP3 Q9BZS1 forkhead box P3 0.99 0.368 0.846
GCG P01275 glucagon 3.5E-02 0.431 0.885
GLUL P15104 glutamate-ammonia ligase Enzyme 1.00 0.513 0.731
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
GSTT1 P30711 glutathione S-transferase theta 1 1.5E-04 0.393 0.923
HLA-B P01889 major histocompatibility complex, class I, B 3.9E-05 0.379 0.885
HLA-DPB1 P04440 major histocompatibility complex, class II, DP beta 1 Immune response 5.3E-10 0.453 0.923
HSD11B1 P28845 hydroxysteroid 11-beta dehydrogenase 1 0.42 0.520 0.731
HSPA4 P34932 heat shock protein family A (Hsp70) member 4 1.00 0.394 0.923
IL22 Q9GZX6 interleukin 22 1.9E-04 0.393 0.885
IL6 P05231 interleukin 6 0.32 0.248 0.962
INS P01308 insulin 0.30 0.445 0.923
KLK3 P07288 kallikrein related peptidase 3 Enzyme 4.4E-06 0.443 0.885
MC2R Q01718 melanocortin 2 receptor G-protein coupled receptor 3.1E-04 0.582 0.654
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
NR0B1 P51843 nuclear receptor subfamily 0 group B member 1 Nuclear receptor 0.97 0.494 0.808
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
NR5A1 Q13285 nuclear receptor subfamily 5 group A member 1 Nuclear receptor 0.99 0.479 0.731