Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
PTGS2 | P35354 | prostaglandin-endoperoxide synthase 2 | Enzyme | 1.00 | 0.314 | 0.962 |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
SMUG1 | Q53HV7 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | 4.5E-04 | 0.322 | 0.923 | |
MYC | P01106 | MYC proto-oncogene, bHLH transcription factor | Transcription factor | 1.00 | 0.344 | 0.923 |
LEP | P41159 | leptin | 0.46 | 0.349 | 0.846 | |
POMC | P01189 | proopiomelanocortin | 1.2E-04 | 0.356 | 0.846 | |
CD44 | P16070 | CD44 molecule (Indian blood group) | 2.4E-07 | 0.363 | 0.962 | |
AGT | P01019 | angiotensinogen | Enzyme modulator | 5.0E-08 | 0.367 | 0.923 |
REN | P00797 | renin | Enzyme | 2.4E-07 | 0.370 | 0.923 |
GH1 | P01241 | growth hormone 1 | Signaling | 3.0E-02 | 0.373 | 0.923 |
ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
ADIPOQ | Q15848 | adiponectin, C1Q and collagen domain containing | 4.6E-09 | 0.376 | 0.885 | |
IGF2 | P01344 | insulin like growth factor 2 | 4.4E-02 | 0.390 | 0.885 | |
RET | P07949 | ret proto-oncogene | Kinase | 1.00 | 0.392 | 0.885 |
HTC2 | hypertrichosis 2 (generalized, congenital) | 0.392 | 0.808 | |||
NR3C1 | P04150 | nuclear receptor subfamily 3 group C member 1 | Nuclear receptor | 0.97 | 0.393 | 0.885 |
SST | P61278 | somatostatin | Signaling | 0.34 | 0.399 | 0.885 |
PRKAR1A | P10644 | protein kinase cAMP-dependent type I regulatory subunit alpha | 1.00 | 0.401 | 0.846 | |
MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
CYP19A1 | P11511 | cytochrome P450 family 19 subfamily A member 1 | Enzyme | 1.7E-05 | 0.410 | 0.885 |